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Ondansetron With Olanzapine for the Treatment of Alcohol Dependence: A Preliminary Clinical Trial

NCT00678457 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2009-01-30

No results posted yet for this study

Summary

This study would like to test whether the combination of ondansetron and olanzapine will be superior to placebo at decreasing self-reported heavy drinking among early onset alcoholics.

Conditions

  • Alcohol Dependence

Interventions

DRUG

Ondansetron

ondansetron (4 μg/kg b.i.d.)

DRUG

Olanzapine

olanzapine (9, 18, and 36 μg/kg)

DRUG

Placebo

placebo

Sponsors & Collaborators

  • University of Virginia

    lead OTHER

Principal Investigators

  • Bankole Johnson, DSc, MD, PhD · University of Virginia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
FACTORIAL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-01-31
Primary Completion
2008-05-31
Completion
2008-05-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00678457 on ClinicalTrials.gov