INCB018424 in Patients With Advanced Hematologic Malignancies
NCT00674479 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 51
Last updated 2025-06-15
Summary
The goal of this clinical research study is to learn if ruxolitinib can help to control advanced hematological malignancies. The safety of this drug will also be studied.
Conditions
- Acute Myeloid Leukemia
- Acute Lymphocytic Leukemia
- Myelodysplastic Syndrome
- Chronic Myelogenous Leukemia
Interventions
- DRUG
-
INCB018424
Starting dose: 25 mg by mouth (po) twice daily for 7 days each week for 4 weeks.
Sponsors & Collaborators
- collaborator INDUSTRY
-
M.D. Anderson Cancer Center
lead OTHER
Principal Investigators
-
Farhad Ravandi-Kashani, M.D. · M.D. Anderson Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-05-12
- Primary Completion
- 2017-03-23
- Completion
- 2017-03-23
- FDA Drug
- Yes
Countries
- United States
Study Locations
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