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A Phase III Intensity Radiotherapy Dose Escalation for Prostate Cancer Using Hypofractionation

NCT00667888 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 225

Last updated 2021-01-25

Study results available
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Summary

The goal of this clinical research study is to compare using external beam radiotherapy with intensity modulated beams for fewer days at a higher dose per day to the same type of therapy for more days at a lower dose per day in the treatment of prostate cancer. The safety of these treatments will also be studied and compared.

Conditions

Interventions

RADIATION

Conventional Fractionated Intensity Modulated Radiotherapy

A total dose of 75.6 Gy will be delivered in 42 fractions to the planning target volume (PTV).

RADIATION

Hypofractionated Intensity Modulated Radiotherapy

A total dose of 72 Gy will be delivered in 30 fractions to the PTV.

Sponsors & Collaborators

  • M.D. Anderson Cancer Center

    lead OTHER

Principal Investigators

  • Deborah A. Kuban, MD · M.D. Anderson Cancer Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2001-01-03
Primary Completion
2015-10-12
Completion
2021-10-31

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00667888 on ClinicalTrials.gov