Use of Multiphoton Microscopy in the Diagnosis of Cancer
NCT00652210 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 344
Last updated 2015-12-10
Summary
Multiphoton microscopy (MPM) has been shown to be able to image tissue at a cellular level. Our project will initially evaluated the ability of MPM imaging to distinguish normal bladder urothelium from atypical and malignant urothelium in the ex vivo setting. After development of sufficient criteria, we plan to develop an endoscopic bladder probe that will provide a non-invasive means to image the interior of the bladder at the cellular level, which would provide direct evidence of the presence of tumor without a biopsy. After exhibiting usefulness of MPM imaging for bladder cancer, we will look at other organs beginning with the colon.
Conditions
Interventions
- OTHER
-
Multiphoton microscopy
Use of multiphoton microscopy to diagnose cancer
Sponsors & Collaborators
-
Weill Medical College of Cornell University
lead OTHER
Principal Investigators
-
Douglas S Scherr, M.D. · Weill Medical College of Cornell University
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 21 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2005-06-30
- Primary Completion
- 2015-09-30
- Completion
- 2015-09-30
Countries
- United States
Study Locations
More Related Trials
-
Prostate Cancer Detection Rate of Targeted Biopsies With PCaVision
NCT06281769 ·Status: COMPLETED ·Phase: NA
-
Micro-Ultrasound/Magnetic Resonance Imaging 001
NCT03938376 ·Status: COMPLETED
-
Multiparametric Ultrasound for the Diagnosis of Clinically Significant Prostate Cancer
NCT06024772 ·Status: NOT_YET_RECRUITING ·Phase: PHASE3
-
MRI in Clinical Staging and Estimation of Treatment Response in Bladder Cancer
NCT02662166 ·Status: COMPLETED ·Phase: NA
-
Urology San Antonio MRI/MicroUS Comparison
NCT03762616 ·Status: COMPLETED ·Phase: NA
-
Bp-MRI Based Multi-planar VI-RADS
NCT06607250 ·Status: COMPLETED
-
Investigation Into Detection of Prostate Cancer Using Voided Urine (Prostate VPAC)
NCT04788277 ·Status: RECRUITING
-
Transperineal Micro-ultrasound for the Detection of Prostate Cancer During Biopsy
NCT07075705 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Diffusion Basis Spectrum Imaging of the Prostate
NCT04420702 ·Status: RECRUITING ·Phase: NA
-
Optimizing Prostate Biopsy Schemes in Men With Multiple mpMRI Visible Lesions
NCT06841211 ·Status: RECRUITING ·Phase: NA
-
Verification of Shear Wave Elastography for DEtection of Prostate Cancer
NCT04836949 ·Status: UNKNOWN ·Phase: NA
-
Imaging of Prostate Cancer Using Two-dimensional MR Spectroscopy and Diffusion Tensor Imaging
NCT00611065 ·Status: WITHDRAWN ·Phase: NA
-
Optimization of Prostate Biopsy - Micro-Ultrasound Versus MRI
NCT05220501 ·Status: COMPLETED ·Phase: NA
-
A Prospective, Randomized Trial Comparing Office-based MR-guided Prostate Biopsy Approaches
NCT03632655 ·Status: TERMINATED ·Phase: NA
-
Circulating Tumor Cells and mpMRI for Non-invasive Diagnosis of Prostate Cancer(CMNDPC)
NCT05947188 ·Status: UNKNOWN ·Phase: NA
-
Multi-Center Trial of High-resolution Transrectal Ultrasound Versus Standard Low-resolution Transrectal Ultrasound for the Identification of Clinically Significant Prostate Cancer
NCT02079025 ·Status: COMPLETED ·Phase: NA
-
Feasibility Study of Ultrasound Elastography Detecting Prostate Cancer
NCT03077126 ·Status: COMPLETED ·Phase: NA
-
Predicting Prostate Biopsy Results With Biomarkers and mpMRI.
NCT03730324 ·Status: COMPLETED ·Phase: NA
-
Non-contrast MR Imaging for Whole Body Cancer Detection and Characterization
NCT03440554 ·Status: UNKNOWN ·Phase: NA
-
Diagnostic Value of MRI-targeted Plus Index-lesion-ipsilaterally Systematic Biopsy for Biopsy-naive Men At Risk of Prostate Cancer
NCT06584279 ·Status: RECRUITING
-
MRI-Guided Biopsy of Recurrent Prostate Cancer After Radiotherapy
NCT00775866 ·Status: COMPLETED ·Phase: NA
-
Comparison of Diagnostic Accuracy of Luminal Index and MP MRI for Accelerated deTEction of Significant Prostate Cancer
NCT05020522 ·Status: RECRUITING ·Phase: NA
-
USPIO-enhanced and Diffusion-weighted MRI for the Detection of Pelvic Lymph Node Metastases
NCT00622973 ·Status: COMPLETED ·Phase: PHASE3
-
Evaluation of Prostate Specific Membrane Antigen Positron Emission Tomography-Computed Tomography in Active Surveillance for Prostate CancEr
NCT05948657 ·Status: RECRUITING ·Phase: NA
-
Multiparametric MRI in Men With Prostate Cancer Undergoing Active Surveillance
NCT02526797 ·Status: ENROLLING_BY_INVITATION