Positron Emission Tomography (PET) Using Hormone Receptor Ligands in Breast Cancer
NCT00647790 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 79
Last updated 2015-08-13
Summary
The purpose of this study is to find a way to learn the hormone receptor status of a tumor before surgery is done. By testing for the hormone receptor proteins, doctors can find out if the breast cancer uses hormones to grow. This is important since the hormone receptor status of a tumor helps doctors decide if extra treatment like chemotherapy or pills are needed.
Conditions
Interventions
- PROCEDURE
-
PET scan with injection of 5-8 mCi of 18FES
Following injection of the tracer 18FES, dynamic images will be obtained for 30 minutes over the chest area to include cardiac region and breasts. Following the first dynamic imaging for 30 minutes, whole body images (base of skull to pelvis) will be obtained at 5 minute/bed position. An additional, longer scan after 60 minutes will be obtained for the chest (1-2-FOV for 15 minutes each). Total time from injection to completion of imaging will be about 90 minutes.
Sponsors & Collaborators
-
United States Department of Defense
collaborator FED -
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Mary Gemignani, MD · Memorial Sloan Kettering Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-11-30
- Primary Completion
- 2013-06-30
- Completion
- 2013-06-30
Countries
- United States
Study Locations
More Related Trials
-
[18F]ISO-1 Positron Emission Tomography (PET/CT) in Primary Breast Cancer
NCT02284919 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Imaging of ER Density to Guide and Improve Tailored Therapy for Acquired Anti-hormonal Resistant Breast Cancer
NCT01088477 ·Status: COMPLETED
-
Imaging of Primary or Recurrent Breast Cancer With 18F-FluorThanatrace PET/CT
NCT03846167 ·Status: ACTIVE_NOT_RECRUITING
-
A Study Comparing Cancer Imaging Approaches in People With Lobular Breast Cancer
NCT06557148 ·Status: RECRUITING
-
An Efficacy and Safety Study to Assess [18F]-ML-10 in Detecting Response of Tumors to Chemotherapy and Radiation
NCT01260480 ·Status: UNKNOWN ·Phase: PHASE2
-
[18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast Cancer
NCT06502691 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
A Study of 1 8F-FDHT PET/MRIScans in Women With Breast Cancer
NCT06145399 ·Status: WITHDRAWN ·Phase: EARLY_PHASE1
-
PET/CT or PET/MRI in Measuring Tumors in Patients Undergoing Clinical Imaging or With Newly Diagnosed Breast Cancer
NCT01892540 ·Status: COMPLETED ·Phase: NA
-
Brain [18F]-FES PET/CT in Patients With Estrogen-Receptor Positive Breast Cancer
NCT06072807 ·Status: RECRUITING ·Phase: PHASE4
-
PET-MR for Prediction and Monitoring of Response to Neoadjuvant Chemotherapy in Breast Cancer
NCT01190566 ·Status: COMPLETED
-
18F-fluoroestradiol (FES) PET/CT for Breast Cancer
NCT04883814 ·Status: UNKNOWN ·Phase: PHASE2
-
F-18 FES PET/CT in Measuring Hormone Expression in Patients With Primary, Recurrent, or Metastatic Breast Cancer Undergoing Endocrine-Targeted Therapy
NCT02149173 ·Status: TERMINATED ·Phase: NA
-
The Value of 18F-FES-PET/CT in Predicting Fulvestrant Efficacy in Breast Cancer
NCT03768479 ·Status: UNKNOWN ·Phase: NA
-
Positron Emission Tomography Imaging Using Copper Cu 64 TP3805 in Patients With Breast Cancer
NCT02810873 ·Status: TERMINATED ·Phase: NA
-
FDG PET and DCE-MRI in Predicting Response to Treatment in Patients With Breast Cancer
NCT01931709 ·Status: TERMINATED ·Phase: NA
-
Study of 18F-FFNP Breast PET/MRI
NCT06086704 ·Status: RECRUITING ·Phase: PHASE2
-
Assessment of Progesterone Receptors in Breast Carcinoma by Positron Emission Tomography (PET) Using Fluoro Furanyl Norprogesterone (FFNP)
NCT00968409 ·Status: COMPLETED ·Phase: PHASE1
-
Clinical Study of 18F-FAPI-RGD in Breast Tumors
NCT05976620 ·Status: COMPLETED
-
PET/MR in Surgical Planning for Breast CA Treated With Neoadj Chemo
NCT04149353 ·Status: TERMINATED ·Phase: NA
-
18F-FLT-PET Imaging of the Brain in Patients With Metastatic Breast Cancer to the Brain Treated With Whole Brain Radiation Therapy With or Without Sorafenib: Comparison With MR Imaging of the Brain
NCT01621906 ·Status: COMPLETED ·Phase: NA
-
[18F]FES PET/CT in Endocrine Refractory Breast Cancer
NCT02409316 ·Status: COMPLETED ·Phase: PHASE2
-
F-18 16 Alpha-Fluoroestradiol-Labeled Positron Emission Tomography in Predicting Response to First-Line Hormone Therapy in Patients With Stage IV Breast Cancer
NCT00602043 ·Status: COMPLETED ·Phase: PHASE2
-
Specimen PET-CT Imaging for Intraoperative Margin Assessment in Breast Cancer
NCT04999917 ·Status: COMPLETED ·Phase: NA
-
Characterizing Breast Cancer With 18F-FES PET/CT
NCT05613270 ·Status: UNKNOWN ·Phase: NA
-
FFNP-PET/MR Imaging of Progesterone Receptor Expression in Invasive Breast Cancer
NCT03212170 ·Status: COMPLETED ·Phase: PHASE2