KX2-391 in Treating Patients With Advanced Solid Tumors or Lymphoma That Did Not Respond to Treatment
NCT00646139 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 7
Last updated 2011-03-02
Summary
RATIONALE: KX2-391 may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
PURPOSE: This phase I trial is studying the side effects and best dose of KX2-391 in treating patients with advanced solid tumors or lymphoma that did not respond to treatment.
Conditions
- Lymphoma
- Lymphoproliferative Disorder
- Small Intestine Cancer
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- DRUG
-
Src kinase inhibitor KX2-391
- OTHER
-
immunoenzyme technique
- OTHER
-
pharmacological study
Sponsors & Collaborators
-
Roswell Park Cancer Institute
lead OTHER
Principal Investigators
-
Alex A. Adjei, MD, PhD · Roswell Park Cancer Institute
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-10-31
- Primary Completion
- 2008-08-31
- Completion
- 2009-03-31
Countries
- United States
Study Locations
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