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rTMS in Treatment of Obsessive Compulsive Disorder (OCD)

NCT00616486 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 24

Last updated 2015-12-16

No results posted yet for this study

Summary

Low frequency (1Hz) rTMS applied bilaterally and simultaneously over SMA for 6 weeks in addition to the standard treatment regimen for OCD, will lead to significant improvement in patients' symptoms. The clinical improvement detected by YBOCS, CGI and SF-36 QOLS scores will be statistically significant in active treatment group compared to sham (placebo) treatment group.

Conditions

  • Obsessive Compulsive Disorder

Interventions

DEVICE

repetitive transcranial magnetic stimulation

6 weeks of stimulation with RMT frequency 1Hz, intensity 110% of RMT for 20 minutes, 5 minutes of trains with 2 minutes of intra-train intervals to both SMA. Treatment will be given 5 times a week for 4 weeks, 3 times a week during Week 5 and 2 times a week during Week 6.

DEVICE

sham (placebo)

Sham treatment will mimic active treatment mentioned above.

Sponsors & Collaborators

  • Military Medical Academy, Bulgaria

    collaborator OTHER

  • Dokuz Eylul University

    collaborator OTHER

  • Queen's University

    lead OTHER

Principal Investigators

  • Roumen Milev, MD · Queen's University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2008-01-31
Primary Completion
2010-05-31
Completion
2012-11-30

Countries

  • Bulgaria
  • Canada
  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00616486 on ClinicalTrials.gov