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Ketamine Compared to Propofol for Pediatric GI Endoscopy

NCT00614159 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 34

Last updated 2009-07-02

No results posted yet for this study

Summary

Elective outpatient endoscopy for children can be safely performed under general anesthesia with either propofol (1) or ketamine (2) infusions. Both infusions have an advantage over general anesthesia with volatile agents because they do not require intubation. The goal of both infusions is to have the patient breath spontaneously without reacting to the endoscopy which is a noxious stimulus. Patient movement, stridor and vomiting are can interrupt the procedure and increase overall OR time. Propofol also carries the added risk of causing apnea. This side effect is not commonly seen with Ketamine. Our hypothesis is that Ketamine's profile makes it a superior drug to Propofol for elective outpatient endoscopy because of reduced profound intra-operative interruptions and faster recovery time. We plan a study of pediatric patients ages 1 to 10 years old undergoing elective outpatient endoscopy. The patients will be randomized to receiving either a Ketamine or Propofol infusion, and the intra-operative interruptions will be documented by the anesthesiologist. The Post Anesthetic Care Unit (PACU) time to recovery will be monitored and recorded by a third party.

Conditions

  • Endoscopy

Interventions

DRUG

Ketamine

Weight based dosage for Peds subjects, used for duration of the endoscopy.

DRUG

Propofol

Weight based dosage for Peds subjects, used for duration of the endoscopy.

Sponsors & Collaborators

  • State University of New York - Upstate Medical University

    lead OTHER

Eligibility

Min Age
1 Year
Max Age
10 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-10-31
Primary Completion
2009-06-30
Completion
2009-06-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00614159 on ClinicalTrials.gov