Trial Outcomes & Findings for HDE Use Protocol of TheraSphere for Treatment of Unresectable HCC (NCT NCT00605150)

NCT ID: NCT00605150

Last Updated: 2022-04-22

Results Overview

Progression of liver cancer

Recruitment status

COMPLETED

Target enrollment

11 participants

Primary outcome timeframe

6 months

Results posted on

2022-04-22

Participant Flow

Total number of patients treated with TheraSphere was 11.

Candidates were selected by the physicians for treatment with TheraSphere, patient's signed informed consent and were treated if they met the criteria for treatment using the Humanitarian Device Exemption (HDE) protocol.

Participant milestones

Participant milestones
Measure
Treatment
TheraSphere, TheraSphere-Yttrium 90 microsphere, treatment for patients with unresectable hepatocellular carcinoma (HCC)
Overall Study
STARTED
11
Overall Study
COMPLETED
10
Overall Study
NOT COMPLETED
1

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

HDE Use Protocol of TheraSphere for Treatment of Unresectable HCC

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
TheraSphere Treatment
n=10 Participants
Total number of patients enrolled, TheraSphere treatment
Age, Categorical
<=18 years
0 Participants
n=99 Participants
Age, Categorical
Between 18 and 65 years
7 Participants
n=99 Participants
Age, Categorical
>=65 years
3 Participants
n=99 Participants
Age, Continuous
60.2 years
STANDARD_DEVIATION 8.509 • n=99 Participants
Sex: Female, Male
Female
1 Participants
n=99 Participants
Sex: Female, Male
Male
9 Participants
n=99 Participants
Region of Enrollment
United States
10 participants
n=99 Participants

PRIMARY outcome

Timeframe: 6 months

Population: Number of participants enrolled

Progression of liver cancer

Outcome measures

Outcome measures
Measure
TheraSphere Treatment
n=11 Participants
Total number of patients enrolled TheraSphere treatment for patients with unresectable HCC
Progression
11 participants

SECONDARY outcome

Timeframe: 6 months

Outcome measures

Outcome measures
Measure
TheraSphere Treatment
n=11 Participants
Total number of patients enrolled TheraSphere treatment for patients with unresectable HCC
Number of Participants With Unacceptable Side Effects After Treatment
0 Participants

Adverse Events

TheraSphere Treatment for Patients With Unresectable HCC

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

David Iannitti, MD

Carolinas Healthcare System

Phone: 704-446-4838

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place