Temozolomide in Treating Patients With Invasive Pituitary Tumors
NCT00601289 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2020-07-31
Summary
RATIONALE: Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
PURPOSE: This phase II trial is studying how well temozolomide works in treating patients with invasive pituitary tumors.
Conditions
Interventions
- DRUG
- GENETIC
-
DNA methylation analysis
- GENETIC
-
microarray analysis
- GENETIC
-
protein expression analysis
- GENETIC
-
proteomic profiling
- OTHER
-
laboratory biomarker analysis
Sponsors & Collaborators
-
Jonsson Comprehensive Cancer Center
lead OTHER
Principal Investigators
-
Anthony Heaney, MD · Jonsson Comprehensive Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-12-31
- Primary Completion
- 2010-10-31
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