Innate Immunity and Respiratory Syncytial Virus (RSV) Infection in Children
NCT00593918 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 91
Last updated 2015-10-20
Summary
In this project we will study the capacity for single nucleotide polymorphisms (SNP) in TLR4 gene to induce varying levels of inflammatory chemokine and cytokine production.
Conditions
- Respiratory Syncytial Virus Infection
Sponsors & Collaborators
-
University of Wisconsin, Madison
lead OTHER
Principal Investigators
-
Theresa W. Guilbert, MD · University of Wisconsin, Madison
Eligibility
- Max Age
- 24 Months
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2003-11-30
- Primary Completion
- 2008-05-31
- Completion
- 2008-06-30
Countries
- United States
Study Locations
More Related Trials
-
Study to Evaluate the Human Infection of the Lower Respiratory Tract in Children at High Risk
NCT00192439 ·Status: COMPLETED
-
A Study to Evaluate the Safety and Ability of the Vaccine to Induce Antibodies Against the Respiratory Syncytial Virus in Healthy Adults
NCT02298179 ·Status: COMPLETED ·Phase: PHASE1
-
Safety Study of a Monoclonal Antibody to Respiratory Syncytial Virus (RSV) in Children Hospitalized With RSV Infection
NCT00192504 ·Status: COMPLETED ·Phase: PHASE1
-
RSV Observational Study 2
NCT01922648 ·Status: COMPLETED
-
Evaluating the Safety and Immune Response to a Respiratory Syncytial Virus (RSV) Vaccine in Adults, RSV-Seropositive Children, and RSV-Seronegative Infants and Children
NCT01459198 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate a Single Intravenous Dose of Motavizumab for the Treatment of Children Hospitalized With Respiratory Syncytial Virus (RSV) Illness
NCT00421304 ·Status: COMPLETED ·Phase: NA
-
Safety and Immunogenicity of the RSV D46cpΔM2-2 Vaccine in RSV-Seropositive Children and RSV-Seronegative Infants and Children
NCT02601612 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of an Ad26.RSV.preF-based Regimen in the Prevention of Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)-Confirmed Respiratory Syncytial Virus (RSV)-Mediated Lower Respiratory Tract Disease in Adults Aged 65 Years and Older
NCT03982199 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Learn About the Safety and Immune Activity of RSVpreF in Children 2 to <18 Years of Age
NCT05900154 ·Status: COMPLETED ·Phase: PHASE1
-
Presatovir in Hematopoietic Cell Transplant Recipients With Respiratory Syncytial Virus (RSV) Infection of the Lower Respiratory Tract
NCT02254421 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Safety, Tolerability and Immunogenicity of an Investigational RSV Vaccine Candidate (Ad26.RSV.preF) in Adults 18 to 50 Years of Age, and RSV-seropositive Toddlers 12 to 24 Months of Age
NCT03303625 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Safety and Immune Response to a Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccine in RSV-Seronegative Infants and Children
NCT02237209 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Efficacy, Immunogenicity, and Safety of RSVpreF in Adults.
NCT05035212 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Immunogenicity of RSV Vaccines in Residents of Long-Term Care Facilities (LTCF)
NCT06077149 ·Status: COMPLETED ·Phase: PHASE4
-
RI-001 in Immunosuppressed Respiratory Syncytial Virus (RSV) Infected Patients at Risk of Lower Tract RSV Illness
NCT00632463 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluating the Safety and Immune Response to a Single Dose of a Respiratory Syncytial Virus (RSV) Vaccine in RSV-Seronegative Infants and Children
NCT01852266 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Pharmacokinetics,and Antiviral Activity of RV299 Against Respiratory Syncytical Virus (RSV)
NCT06067191 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Describe the Safety and Immunogenicity of a RSV Vaccine in Healthy Adults
NCT03529773 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluating the Infectivity, Safety and Immunogenicity of Respiratory Syncytial Virus Vaccines, RSV 6120/∆NS1 and RSV 6120/F1/G2/∆NS1, in RSV-Seropositive Children and RSV-Seronegative Infants and Children
NCT03596801 ·Status: COMPLETED ·Phase: PHASE1
-
Evaluating the Infectivity, Safety and Immunogenicity of a Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine, LID/ΔM2-2/1030s, in RSV-Seronegative Infants and Children 6 to 24 Months of Age
NCT04520659 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Assess Safety, Tolerability and Immunogenicity of RSVpreF From Multidose Vials in Healthy Female Adults.
NCT06473519 ·Status: COMPLETED ·Phase: PHASE3
-
Novel Mucosal Correlates Of RSV Protection In Older Adults
NCT06274619 ·Status: COMPLETED ·Phase: NA
-
Safety, Tolerability, and Pharmacokinetics of RSV Monoclonal Antibody RSM01 in Healthy Adults
NCT05118386 ·Status: COMPLETED ·Phase: PHASE1
-
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Safety of MEDI-559 in Healthy 1 to <24 Month-Old Children
NCT00767416 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Phase I, Randomized, Double-Blind, Single-Dose, Dose Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of MEDI-557
NCT00578682 ·Status: COMPLETED ·Phase: PHASE1