Psychological Influences on Postoperative Recovery

Summary

The primary hypothesis tested in this project is that the preoperative behavioral stress response predicts postoperative behavioral and clinical recovery of children undergoing surgery.

Conditions

• Care, Postoperative
• Pain, Postoperative
• Surgical Procedures, Operative
• Otorhinolaryngologic Surgical Procedures
• Tonsillectomy
• Adenoidectomy

Interventions

BEHAVIORAL

Preoperative Preparation Program (Child Life Specialist)

This group will receive the standard preoperative visit to the hospital with Child Life intervention

DRUG

Midazolam

0.5 mg/kg oral midazolam

BEHAVIORAL

Parental Presence during Induction of Anesthesia

One parent will be present during induction of anesthesia of the child. The parent will be accompanied out of the OR by a nurse once the induction is completed. These parents will have completed a parent preparation program.

OTHER

PPIA preparation program PLUS Midazolam premedication

Subjects in this group will receive both interventions 2 and 3.

Sponsors & Collaborators

• National Institutes of Health (NIH)

  collaborator NIH

• Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

  collaborator NIH

• University of California, Irvine

  lead OTHER

Principal Investigators

• Zeev N Kain, MD, MBA · Yale University Department of Anesthesiology

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

NONE

Model

FACTORIAL

Eligibility

Min Age

3 Years

Max Age

12 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2003-04-30

Primary Completion

2009-04-30

Completion

2009-04-30

Countries

• United States

Study Locations