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Comparison of Two Multi-Purpose Solution and Lens Material Combinations on Corneal Barrier Function

NCT00560898 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2008-05-20

No results posted yet for this study

Summary

The purpose of this study is to measure the relative "barrier" function of the top layer of the cornea (called the epithelium), or the degree to which the cornea can prevent the penetration of the colored dye sodium fluorescein into the eye. This is a clinical investigation of the effect on corneal barrier function following wear of two contact lens materials and two contact lens care systems, approved for marketing in the US by the Food and Drug Administration. These contact lenses will be worn for two hours, following soak in one of two marketed contact lens disinfecting solutions. Approximately 25 young, adapted contact lens wearers will participate.

Conditions

  • Contact Lens Disinfecting Solutions

Interventions

DRUG

ProClear Lens Material soaked in ReNu Multiplus Multipurpose Solution

Contact lens soaked in multipuprpose solution for 8 hours, then worn for two hours

DRUG

Acuvue Advance Lens Material soaked in ReNu Multiplus Multipurpose Solution

Contact lens soaked in multipuprpose solution for 8 hours, then worn for two hours

DRUG

Acuvue Advance Lens Material soaked in Optifree RepleniSH Multipurpose Solution

Contact lens soaked in multipuprpose solution for 8 hours, then worn for two hours

DRUG

ProClear Lens Material soaked in Optifree RepleniSH Multipurpose Solution

Contact lens soaked in multipuprpose solution for 8 hours, then worn for two hours

Sponsors & Collaborators

  • Alcon Research

    collaborator INDUSTRY

  • Southern California College of Optometry at Marshall B. Ketchum University

    lead OTHER

Principal Investigators

  • Jerry R Paugh, OD, PhD · Southern California College of Optometry at Marshall B. Ketchum University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-09-30
Primary Completion
2007-12-31
Completion
2008-03-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00560898 on ClinicalTrials.gov