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Sunscreen and After-sun-lotion Protection in Polymorphic Light Eruption

NCT00549588 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 14

Last updated 2009-09-30

No results posted yet for this study

Summary

Polymorphic light eruption (PLE) is a common photodermatosis characterized by the appearance of itching, erythema, papules or vesicles on sun-exposed skin. Though etiology is unclear it is hypothesized that it is an abnormal immune response to autologous antigens generated by ultraviolet radiation (UVR). This randomized, double blinded left-right body side experimental comparison study was designed to assess the preventive effect of a sunscreen and topical DNA repair enzyme-containing after-sun lotion in PLE.

Conditions

  • Polymorphic Light Eruption

Interventions

OTHER

After-sun-lotion with DNA repair enzymes

2 mg/cm2 immediately after UV exposure

OTHER

SPF30 sunscreen

2 mg/cm2 2o min before UV exposure

OTHER

Placebo after-sun-lotion

2mg/cm2 immediately after UV exposure

OTHER

Intervention: none (only UV)

Sponsors & Collaborators

  • Medical University of Graz

    lead OTHER

Principal Investigators

  • Peter Wolf, MD · Medical University of Graz

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
19 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-02-29
Primary Completion
2004-06-30
Completion
2006-08-31

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00549588 on ClinicalTrials.gov