Home-Based Assessment for Alzheimer Disease Prevention

Summary

The purpose of this study is to evaluate three methods of performing home-based assessments in Alzheimer's Disease (AD) prevention trials. The initial in-person assessment will be done in the clinic or at home.

Conditions

• Mild Cognitive Impairment
• Alzheimer's Disease

Interventions

BEHAVIORAL

Mail and Live Phone

This group will receive assessments of all domains by mail, except for the cognitive performance assessment which will be administered via phone by a live, trained evaluator. Medication compliance will be monitored by a written medication log which will be returned by mail with the other mail-in assessments.

BEHAVIORAL

Interactive Voice Response (IVR)

In this group, participants will be asked to answer questions via an automated phone system using interactive voice recognition (IVR) and key-pad response entry. Medication compliance will be monitored by the same method. A standard large-key telephone and training in the use of the interactive phone system will be provided to all participants.

BEHAVIORAL

Home-based Computer Kiosk

Participants at entry will receive a special Kiosk-like device for collecting assessment information and will be taught to use this device. The user interface will consist of a monitor with a touch screen and a telephone handset, similar to what is often used in museum displays. Pre-recorded instructions will be delivered through the handset as well as displayed visually on the screen. Data will be collected using the handset's high-quality microphone. Daily activity assessments of timed medication use will be obtained via an automated medication tracking device.

BEHAVIORAL

Traditional Evaluation Instruments

Evaluation methods typically used in clinical trials

Sponsors & Collaborators

• National Institute on Aging (NIA)

  collaborator NIH

• Alzheimer's Disease Cooperative Study (ADCS)

  lead OTHER

Principal Investigators

• Mary Sano, PhD · Mount Sinai Medical School

Study Design

Allocation

RANDOMIZED

Purpose

SCREENING

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

75 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2007-09-30

Primary Completion

2013-06-30

Completion

2013-06-30

Countries

• United States

Study Locations