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Calibrating Imaging Techniques to Study Blood Flow

NCT00546091 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2017-10-06

No results posted yet for this study

Summary

This study will explore the uses of three noninvasive imaging techniques-thermography, laser Doppler imaging, and multispectral imaging-to test the blood flow of healthy volunteers. By comparing these three techniques, researchers will be able to train these imaging systems to better evaluate skin types and blood flow. The study will also test computer programs that have been developed to correct for the effects of curvature and body hair on the images.

Healthy volunteers must be older than 18 years of age and may not have had a history of malignant tumors, skin disease, or vascular disease.

Participants will undergo the following procedures on an outpatient basis:

Three different types of images taken of the participant s forearm

* Thermography infrared thermal imaging to map skin temperature
* Laser Doppler imaging low-powered laser imaging to map blood flow in the skin
* Multispectral imaging near-infrared light imaging to measure total blood flow and oxygen levels in the skin

A reactive hyperemia experiment, in which multispectral images will be taken of the participant s forearm during and after the use of a blood pressure cuff

A hair removal experiment, in which images will be collected of the participant s forearm in separate scans done before and after the hair is removed with a topical hair removal solution

The entire series of exams will take approximately one hour to perform.

Conditions

  • Healthy Volunteers Only

Sponsors & Collaborators

  • Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

    lead NIH

Principal Investigators

  • Amir Gandjbakhche, Ph.D. · Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-10-15
Completion
2012-10-19

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00546091 on ClinicalTrials.gov