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Transient Osteoporosis of Pregnancy: A Possible Peptide Mediator

NCT00541645 · Status: SUSPENDED · Type: OBSERVATIONAL

Last updated 2008-03-18

No results posted yet for this study

Summary

Transient osteoporosis of pregnancy (TOoP) is uncommonly encountered in orthopedic and obstetric practice, with most reports consisting of single cases.

This rare condition consists of significant osteoporosis affecting the hips and spine, causing significant morbidity, and putting young female patients at risk for vertebral and femoral neck fractures.

The pathogenesis of transient osteoporosis of pregnancy is unknown, with various theories as to its etiology.

Recently, a number of reports have described elevated levels of PTHrP in patients with transient osteoporosis in pregnancy and of the postpartum period Our goal in this study is to assess the role of PTHrP in transient osteoporosis of pregnancy

Conditions

  • Transient Osteperosis

Sponsors & Collaborators

  • Hadassah Medical Organization

    lead OTHER

Principal Investigators

  • Efrain Liebner, MD · Hadassah Medical Organization

  • Meir Liebergall, M.D · Hadassah Medical Organization

  • Tzvi Bar-Shavit, Ph.D · The Hebrew University

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00541645 on ClinicalTrials.gov