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Effects of Coenzyme Q10 on Charcot-Marie-Tooth Disease

NCT00541164 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2013-07-15

No results posted yet for this study

Summary

The object of this research is to test the effectiveness of Coenzyme Q10 (CoQ10) on symptoms of weakness, fatigue, and pain in persons with Charcot-Marie-Tooth disease (CMT).In this study we also intend to examine the impact of daily supplementation on overall quality of life.We are also interested in identifying any differences in serum ratios of CoQ10 in the oxidized and reduced forms.

Conditions

  • Charcot Marie Tooth Disease

Interventions

DRUG

Coenzyme Q10

300 mg CoQ10 twice a day for 48 weeks

DIETARY_SUPPLEMENT

Coenzyme Q10

300mg CoQ10 twice a day for 24 weeks beginning at week 24 of the study

Sponsors & Collaborators

  • United States Department of Defense

    collaborator FED

  • Memorial Medical Center

    lead OTHER

Principal Investigators

  • Sharon Plank, MD · John P. Murtha Neuroscience and Pain Institute

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-09-30
Primary Completion
2013-01-31
Completion
2013-01-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00541164 on ClinicalTrials.gov