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Effectiveness of Oral Quinine and Artemether-Lumefantrine in the Treatment of Uncomplicated Malaria in Ugandan Children

NCT00540202 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 302

Last updated 2007-10-05

No results posted yet for this study

Summary

We will test the hypothesis that there is a difference in effectiveness of oral quinine in comparison to artemether Lumefantrine in the treatment of uncomplicated malaria in children.

Conditions

  • Uncomplicated Malaria

Interventions

DRUG

artemether-lumefantrine

Tablets taken twice daily for 3 days according to weight based guidelines.

DRUG

Oral quinine

Quinine tablets given at 10mg/kg 8 hourly for 7 days

Sponsors & Collaborators

  • Ministry of Health, Uganda

    collaborator OTHER_GOV

  • Uganda Malaria Surveillance Project

    collaborator OTHER

  • Makerere University

    lead OTHER

Principal Investigators

  • Ambrose O Talisuna, PhD · Ministry of Health, Uganda

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
6 Months
Max Age
5 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-09-30
Completion
2008-04-30

Countries

  • Uganda

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00540202 on ClinicalTrials.gov