MedTrace Logo

Diagnostics for the Reperfusion Injury Following MI

NCT00529607 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 200

Last updated 2009-03-20

No results posted yet for this study

Summary

The primary purpose of this study is to correlate new cardiac imaging modalities (2D, 3D echocardiography, contrast echocardiography, strain analysis and cardiac MRI) to biochemical parameters as the L-arginine-nitric oxide pathway and inflammatory cascades to characterize the reperfusion injury following myocardial infarction and thus providing a basis for further diagnostic and therapeutic approaches.

Conditions

  • Reperfusion Injury

Interventions

DRUG

contrast echocardiography

directly after PCI, at 24 h after PCI, before discharge and at 6 months

PROCEDURE

2D and 3D echocardiography

directly after PCI, at 24 h after PCI, before discharge and at 6 months

PROCEDURE

cardiac MRI

before discharge and after 6 months

PROCEDURE

blood sampling

routine lab work plus infarction and inflammation biomarkers 1: before PCI, after PCI, at 34 hours, at discharge, at 6 months 2 and 3: one blood sample in total before PCI in 2 and at any time in 3

Sponsors & Collaborators

  • RWTH Aachen University

    lead OTHER

Principal Investigators

  • Wolfgang Lepper · Department of Medicine, Division of Cardiology, Pulmonary Diseases and Vascular Medicine at the University Hospital, RWTH Aachen

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-09-30
Primary Completion
2009-03-31
Completion
2009-03-31

Countries

  • Germany

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00529607 on ClinicalTrials.gov