Suicide Prevention by Lithium - the Lithium Intervention Study

Summary

The purpose of this study is to examine the proposed suicide preventive effects of lithium in a randomized controlled trial within a group of individuals with depressive disorders. The hypothesis being tested is that lithium treatment will significantly reduce the risk for another suicide attempt.

Conditions

• Suicide
• Depressive Disorders

Interventions

DRUG

lithium

DRUG

placebo

Sponsors & Collaborators

• German Federal Ministry of Education and Research

  collaborator OTHER_GOV

• Sanofi

  collaborator INDUSTRY

• Technische Universität Dresden

  collaborator OTHER

• University of Bonn

  collaborator OTHER

• Charite University, Berlin, Germany

  collaborator OTHER

• University of Erlangen-Nürnberg

  collaborator OTHER

• University Hospital Schleswig-Holstein

  lead OTHER

Principal Investigators

• Fritz Hohagen, Prof. · Department of Psychiatry and Psychotherapy, Universitätsklinikum Schleswig-Holstein, Campus Luebeck

• Bruno Müller-Oerlinghausen, Prof. · Former Research Group Clinical Psychopharmacology, Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin

• Werner Felber, Prof. · Department of Psychiatry and Psychotherapy, Medizinische Fakultät der Technischen Universität Dresden

• Bernd Ahrens, PD · Department of Psychiatry and Psychotherapy, Universitätsklinikum Schleswig-Holstein, Campus Luebeck

• Erik Lauterbach, Dr. · Department of Psychiatry and Psychotherapy, Universitätsklinikum Schleswig-Holstein, Campus Luebeck

• Thomas Bronisch, Prof. · Max-Planck-Institute of Psychiatry Munich

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2001-01-31

Completion

2006-06-30

Countries

• Germany

Study Locations