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Optimal Dose of Omeprazole After Endoscopic Treatment of Bleeding Peptic Ulcers

NCT00519519 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 126

Last updated 2017-02-10

No results posted yet for this study

Summary

Bleeding peptic ulcers are one of the major causes of morbidity and mortality for hospital emergency admissions.The initial treatment is endoscopic therapy followed by intravenous omeprazole. However the optimal dosage of omeprazole is not known. We conducted this study to find out the optimal dosage in such clinical scenario.

Conditions

  • Bleeding Peptic Ulcers Disease

Interventions

DRUG

Omeprazole

intravenous 80mg bolus followed by 8mg / hr for 3 days

Sponsors & Collaborators

  • Singapore General Hospital

    lead OTHER

Principal Investigators

  • Weng Hoong Chan, MBBS, FRCS · Singapore General Hospital

  • Weng Hoong Chan, MBBS, FRCS · Department of Surgery, Singapore General Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-07-31
Primary Completion
2007-10-31
Completion
2007-11-30

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00519519 on ClinicalTrials.gov