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Left Atrial Remodelling in Hypertension: Effects of Ramipril or Irbesartan

NCT00517322 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2007-08-16

No results posted yet for this study

Summary

Aim of the study is to compare in hypertensive patients the effect of one year therapy with ACE-inhibitor (RAMIPRIL) or angiotensin II receptor blocker (IRBESARTAN) on left atrial remodelling and diastolic function.

Conditions

  • Left Atrial Volume
  • Hypertensive Heart Disease
  • Antihypertensive Drugs
  • Diastolic Function
  • Renin Angiotensin System

Interventions

DRUG

ramipril

ramipril 2.5- 5 mg once daily

DRUG

irbesartan

irbesartan 150-300 mg once daily

Sponsors & Collaborators

  • Università degli Studi dell'Insubria

    lead OTHER

Principal Investigators

  • anna maria grandi, MD · Università degli Studi dell'Insubria

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-08-31
Completion
2010-08-31

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00517322 on ClinicalTrials.gov