Calcium, Probiotics and Acute Diarrheal Disease Among Indonesian Children

Summary

This is a long term study on the efficacy of dietary calcium with or without probiotic strains in reducing the mean number of episodes and duration of diarrheal disease.

Conditions

• Healthy
• Diarrhea

Interventions

DIETARY_SUPPLEMENT

low calcium milk of 180 ml

twice daily for 24 weeks

DIETARY_SUPPLEMENT

regular milk of 180 ml

twice daily for 24 weeks

DIETARY_SUPPLEMENT

regular milk of 180 ml + probiotics

twice daily for 24 weeks

DIETARY_SUPPLEMENT

regular milk of 180 ml + probiotics

twice daily for 24 weeks

Sponsors & Collaborators

• Top Institute Food and Nutrition

  collaborator OTHER

• SEAMEO-TROPMED RCCN University of Indonesia

  collaborator UNKNOWN

• Wageningen University

  lead OTHER

Principal Investigators

• Rina Agustina, MD · SEAMEO-TROPMED RCCN UI

• Frans J. Kok, Prof · Division of Human Nutrition, Wageningen University (WUR)

• Ingeborg Bovee-Oudenhoven, PhD · TIFN/ NIZO Food Research

• Agus Firmansyah, Prof, MD · Faculty of Medicine University of Indonesia

• Widjaja Lukito, MD · SEAMEO-TROPMED RCCN UI

Study Design

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Model

PARALLEL

Eligibility

Min Age

1 Year

Max Age

6 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2007-08-31

Primary Completion

2008-09-30

Completion

2008-09-30

Countries

• Indonesia

Study Locations