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Transfusion Alternatives Pre-operatively in Sickle Cell Disease (TAPS)

NCT00512577 · Status: TERMINATED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 70

Last updated 2023-03-23

No results posted yet for this study

Summary

TAPS is a sequential trial which aims to investigate whether the administration of a blood transfusion pre-operatively to patients with sickle cell disease (HB SS or Hb SB0 thal)having low or medium risk elective surgery increases or decreases the overall rate of peri-operative complications. The proportion of patients with peri-operative complications in two randomised groups of transfused and untransfused patients will be compared.

Conditions

Interventions

OTHER

Red blood cell transfusion

Pre-operative red blood cell transfusion

Sponsors & Collaborators

  • British Medical Research Council

    collaborator OTHER_GOV

  • University of York

    collaborator OTHER

  • NHS Blood and Transplant

    lead OTHER_GOV

Principal Investigators

  • Lorna M Williamson, MRCP,MRCPath · University of Cambridge and NHSBT

  • Sally C Davies, MRCP,MRCPath · Imperial College, University of London and Central Middlesex Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
1 Year
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-07-31
Primary Completion
2011-03-31
Completion
2011-03-31

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00512577 on ClinicalTrials.gov