Filgrastim-Mobilized Peripheral Blood Stem Cells for Allogeneic Transplantation With Unrelated Donors
NCT00511550 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 15
Last updated 2008-03-05
Summary
Peripheral blood stem cells (PBSCs) collected following stimulation with filgrastim are commonly used for autologous hematopoietic transplants. PBSCs are also now being used for some syngeneic and allogeneic hematopoietic transplants involving HLA-matched sibling donors. However, many issues remain unanswered about the use of PBSCs for allogeneic transplants and the effects of filgrastim on healthy individuals. The purpose of this study is to determine the effectiveness of filgrastim stimulated PBSCs in hematopoietic cell transplants involving unrelated donors and to determine the effects of this donation process on unrelated stem cell donors.
Conditions
- Healthy
Sponsors & Collaborators
-
University of California, San Francisco
lead OTHER
Principal Investigators
-
Thomas G. Martin, M.D. · University of California, San Francisco
-
John Miller, M.D.,Ph.D. · National Marrow Donor Program
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2005-08-31
- Completion
- 2007-11-30
Countries
- United States
Study Locations
More Related Trials
-
Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
NCT01076270 ·Status: TERMINATED ·Phase: NA
-
Unrelated Stem Cell Transplantation for Adults With Hematopoietic Disorders
NCT00511537 ·Status: COMPLETED
-
A Clinical Study of Autologous Peripheral Blood Stem Cell Mobilization for PEG-G-CSF
NCT05409547 ·Status: UNKNOWN ·Phase: PHASE4
-
Nonmyeloablative Hematopoietic Cell Transplantation (HCT) for Patients With Hematologic Malignancies Using Related, HLA-Haploidentical Donors: A Pilot Trial of Peripheral Blood Stem Cells (PBSC) as the Donor Source
NCT02167958 ·Status: COMPLETED ·Phase: PHASE1
-
Busulfan, Cyclophosphamide, & Antithymocyte Globulin Followed by Stem Cell Transplant in Treating Hematologic Cancer
NCT00611351 ·Status: COMPLETED ·Phase: PHASE2
-
Stem Cell Mobilization Potential in Patients With Aplastic Anemia in Remission
NCT00011830 ·Status: COMPLETED ·Phase: PHASE1
-
Sargramostim in Reducing Graft-Versus-Host Disease in Patients Who Are Undergoing Donor Stem Cell Transplantation for Hematologic Cancer or Aplastic Anemia
NCT00053157 ·Status: COMPLETED ·Phase: NA
-
Peripheral Blood Stem Cell Transplantation (PBSCT)From Haploidentical Related Donors
NCT00618969 ·Status: COMPLETED ·Phase: PHASE2
-
Peripheral Stem Cell Transplantation Plus Filgrastim in Treating Patients With Acute or Chronic Myelogenous Leukemia
NCT00002833 ·Status: COMPLETED ·Phase: PHASE2
-
Infliximab for the Prevention of Graft-versus-Host Disease Following Allogenic Hematopoietic Stem Cell Transplantation
NCT00201799 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation
NCT02356159 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases
NCT00006055 ·Status: UNKNOWN ·Phase: NA
-
Evaluation of Pegfilgrastim for Stem Cell Mobilization in Children
NCT00695370 ·Status: TERMINATED ·Phase: PHASE2
-
Methods to Enhance the Safety and Effectiveness of Stem Cell Transplants
NCT00378534 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Opebacan in Patients Undergoing Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)
NCT00454155 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders
NCT00544115 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Collection of Bone Marrow From Donors Treated With or Without Filgrastim
NCT01149096 ·Status: COMPLETED ·Phase: PHASE3
-
Donor Umbilical Cord Blood Transplantation in Treating Patients With Leukemia, Lymphoma, or Nonmalignant Hematologic Disorders
NCT00055653 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of PEG-rhG-CSF and rhG-CSF Used for Aplastic Anemia Granulocyte Deficiency
NCT05531279 ·Status: RECRUITING ·Phase: NA
-
Donor Stem Cell Transplant or Donor White Blood Cell Infusions in Treating Patients With Hematologic Cancer
NCT00281879 ·Status: TERMINATED ·Phase: PHASE2
-
Granulocyte Colony Stimulating Factor (G-CSF) for Bone Marrow Transplant (BMT)
NCT00231309 ·Status: COMPLETED ·Phase: NA
-
Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies.
NCT00890500 ·Status: COMPLETED ·Phase: PHASE1
-
Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT
NCT00516152 ·Status: COMPLETED ·Phase: PHASE2
-
Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer, Metastatic Kidney Cancer, or Aplastic Anemia
NCT00295997 ·Status: UNKNOWN ·Phase: NA
-
Allogeneic Transplantation for Patients With Acute Leukemia or Chronic Myelogenous Leukemia (CML)
NCT00185523 ·Status: TERMINATED