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Catecholamines Can Attenuate Intermittent Hypoxia-Induced Expression of TNF in Human Monocytes

NCT00498862 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 15

Last updated 2007-07-10

No results posted yet for this study

Summary

Specific aim To examine the effect of catecholamines on the modulation of intermittent hypoxia induced TNF- in human monocytes from both healthy subjects and OSA patients (2). To map the signaling pathway of catecholamines regulating the intermittent hypoxia induced TNF- expression.

(3). To explore the potential therapeutic effects of  or  agonists/antagonists on intermittent hypoxia induced TNF- expression

Conditions

  • Healthy

Sponsors & Collaborators

  • National Taiwan University Hospital

    lead OTHER

Principal Investigators

  • Peiln Lee, M.D. · National Taiwan Univerisity Hospital

  • Peilin Lee, M.D. · National Taiwan University Hospital

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-09-30

Countries

  • Taiwan

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00498862 on ClinicalTrials.gov