AZD1152 in Patients With Advanced Solid Malignancies-Study 1
NCT00497731 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 70
Last updated 2009-06-22
Summary
The primary purpose of this protocol is to investigate the safety and tolerability of AZD1152 when given as a continuous 2-hour infusion every week and every 2 weeks in patients with advanced solid malignancies.
Conditions
Interventions
- DRUG
-
AZD1152
2-hour continuous intravenous infusion
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Jan Schellens, MD · NKI
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-05-31
- Primary Completion
- 2008-06-30
- Completion
- 2009-04-30
Countries
- Netherlands
Study Locations
More Related Trials
-
A Study of AZD0466 in Patients With Advanced Hematologic or Solid Tumors
NCT04214093 ·Status: TERMINATED ·Phase: PHASE1
-
Study of AZD0466 Monotherapy or in Combination in Patients With Advanced Haematological Malignancies
NCT04865419 ·Status: TERMINATED ·Phase: PHASE1
-
Study is Designed to Assess the Safety and Tolerability of AZD4547 at Increasing Doses in Patients With Advanced Tumours
NCT00979134 ·Status: TERMINATED ·Phase: PHASE1
-
Phase I Study of AZD2171 co-Administered With Fixed Multiple Oral Doses of ZD1839 in Patients With Advanced Cancer
NCT00502060 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I Study in Patients With Solid Tumours
NCT00496028 ·Status: COMPLETED ·Phase: PHASE1
-
AZD5438 in Patients With Advanced Solid Malignancies
NCT00088790 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Assess the Safety and Preliminary Efficacy of AZD0156 at Increasing Doses Alone or in Combination With Other Anti-cancer Treatment in Patients With Advanced Cancer
NCT02588105 ·Status: COMPLETED ·Phase: PHASE1
-
AZD5153 in Patients With Relapsed or Refractory Solid Tumors, Including Lymphomas
NCT03205176 ·Status: COMPLETED ·Phase: PHASE1
-
AZD8330 First Time in Man in Patients With Advanced Malignancies
NCT00454090 ·Status: COMPLETED ·Phase: PHASE1
-
Phase Ib Study to Determine MTD of AZD1775 Monotherapy in Patients With Locally Advanced or Metastatic Solid Tumours.
NCT02610075 ·Status: COMPLETED ·Phase: PHASE1
-
Global Phase1 Study to Assess the Safety and Tolerability of AZD1208 in Advanced Solid Tumors and Malignant Lymphoma
NCT01588548 ·Status: COMPLETED ·Phase: PHASE1
-
Study of AZD8931 in Patients With Advanced Solid Malignancies
NCT00637039 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I Single Ascending Dose/Multiple Ascending Dose in Patients Treated With AZD7762 and Irinotecan
NCT00473616 ·Status: TERMINATED ·Phase: PHASE1
-
Phase I, Open-label, Dose-escalation, Safety and PK Study of AZD6918
NCT00733031 ·Status: TERMINATED ·Phase: PHASE1
-
Phase I, Open-Label, Dose-Escalation Study of AZD4877 in Solid Tumors
NCT00389389 ·Status: COMPLETED ·Phase: PHASE1
-
AZD9150 Plus Durvalumab Alone or in Combination With Chemotherapy in Patients With Advanced, Solid Tumours and in Patients With Non-Small-Cell Lung Cancer
NCT03421353 ·Status: COMPLETED ·Phase: PHASE1
-
A Pharmacokinetic and Pharmacodynamic Study of DZ-002 in Patients With Advanced Solid Malignancies or Lymphoma
NCT04970992 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment Schedules
NCT01226316 ·Status: COMPLETED ·Phase: PHASE1
-
Study of AZD9150 and MEDI4736 (Durvalumab) in Japanese Adult Patients With Advanced Solid Malignancies
NCT03394144 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Tolerability Study of AZD2171 in Combination With AZD0530 in Patients With Advanced Solid Tumours
NCT00475956 ·Status: COMPLETED ·Phase: PHASE1
-
Safety, Tolerability and Pharmacokinetics of AZD1775 (Adavosertib) Plus MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumours
NCT02617277 ·Status: COMPLETED ·Phase: PHASE1
-
Preliminary Anti-tumour Activity of mTor Kinase Inhibitor in Advanced Tumours
NCT01194193 ·Status: WITHDRAWN ·Phase: PHASE1
-
An Open-Label Dose-Escalation Study to Evaluate XmAb24306 as a Single Agent and in Combination With Atezolizumab in Participants With Locally Advanced or Metastatic Solid Tumors
NCT04250155 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Phase I, Dose-Escalation Study to Assess the Safety and Drug Levels in Blood of AZD4877 in Japanese Adult Patients
NCT00613652 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I Study With AZD2171 in Patients With Advanced Solid Malignant Tumors and Liver Metastases
NCT00501605 ·Status: COMPLETED ·Phase: PHASE1