MedTrace Logo

High Versus Low Dose Supplemental External Radiation With Pd-103 for Prostate Cancer

NCT00494546 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 568

Last updated 2007-06-29

No results posted yet for this study

Summary

Objective: The objective of this study is test the hypothesis that delivering a higher percentage of the radiation dose as external radiation versus implant will lead to higher tumor control rates.

Research design A total of 600 patients with AJC clinical stage T1-T2 prostatic carcinoma (Gleason grade 7 to 10 and/or PSA 10 to 20 ng/ml) will be randomized to treatment with 44 Gy versus 20 Gy external radiation plus a Pd-103 implant boost (90 Gy versus 105 Gy, respectively).

Conditions

Interventions

PROCEDURE

Pd-103 with 20 vs 44 Gy supplemental beam XRT

Sponsors & Collaborators

  • Schiffler Cancer Center

    collaborator OTHER

  • VA Puget Sound Health Care System

    lead FED

Principal Investigators

  • Kent E Wallner, MD · Puget Sound Health Care system

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
1999-01-31
Completion
2007-06-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00494546 on ClinicalTrials.gov