Talabostat in Treating Patients With Metastatic Kidney Cancer
NCT00489710 · Status: WITHDRAWN · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2023-08-22
Summary
RATIONALE: Talabostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
PURPOSE: This phase II trial is studying how well talabostat works in treating patients with metastatic kidney cancer.
Conditions
Interventions
- DRUG
-
talabostat mesylate
- BIOLOGICAL
-
enzyme inhibitor therapy
- DIAGNOSTIC_TEST
-
flow cytometry
- DIAGNOSTIC_TEST
-
laboratory biomarker analysis
- BIOLOGICAL
-
non-specific immune-modulator therapy
Sponsors & Collaborators
-
University of Nebraska
lead OTHER
Principal Investigators
-
Ralph Hauke, MD · University of Nebraska
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 19 Years
- Max Age
- 120 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-12-31
- Primary Completion
- 2007-05-30
- Completion
- 2007-05-30
More Related Trials
-
Interleukin-2, Vinblastine, and GM-CSF in Treating Patients With Metastatic Kidney Cancer
NCT00003181 ·Status: UNKNOWN ·Phase: PHASE2
-
Measuring the Effects of Talazoparib in Patients With Advanced Cancer and DNA Repair Variations
NCT04550494 ·Status: RECRUITING ·Phase: PHASE2
-
Cabozantinib in Treating Patients With Locally Advanced or Metastatic Unresectable Adrenocortical Carcinoma
NCT03370718 ·Status: COMPLETED ·Phase: PHASE2
-
Talazoparib and Avelumab in Participants With Metastatic Renal Cell Carcinoma
NCT04068831 ·Status: COMPLETED ·Phase: PHASE2
-
Thalidomide in Treating Patients With Recurrent or Metastatic Head and Neck Cancer
NCT00003850 ·Status: COMPLETED ·Phase: PHASE2
-
Chemotherapy in Treating Patients With Metastatic Kidney Cancer
NCT00024388 ·Status: UNKNOWN ·Phase: PHASE2
-
Trametinib in Treating Patients With Epithelioid Hemangioendothelioma That is Metastatic, Locally Advanced, or Cannot Be Removed by Surgery
NCT03148275 ·Status: COMPLETED ·Phase: PHASE2
-
A Trial of Thalidomide and Capecitabine in Metastatic Renal Cell Carcinoma
NCT00226980 ·Status: COMPLETED ·Phase: PHASE2
-
Testing Cabozantinib With or Without Atezolizumab in Patients With Advanced Papillary Kidney Cancer, PAPMET2 Trial
NCT05411081 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Tazemetostat in Treating Patients With Metastatic or Unresectable Solid Tumors or B-Cell Lymphomas With Liver Dysfunction
NCT03217253 ·Status: WITHDRAWN ·Phase: PHASE1
-
Capecitabine in Treating Patients With Malignant Mesothelioma
NCT00004183 ·Status: COMPLETED ·Phase: PHASE2
-
17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Metastatic Malignant Melanoma
NCT00104897 ·Status: COMPLETED ·Phase: PHASE2
-
Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes
NCT02286687 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Temozolomide in Treating Patients With Metastatic Non-small Cell Lung Cancer
NCT00006877 ·Status: COMPLETED ·Phase: PHASE2
-
Nintedanib in Treating Patients With Locally Advanced or Metastatic Neuroendocrine Tumors
NCT02399215 ·Status: COMPLETED ·Phase: PHASE2
-
Study of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid Tumors
NCT03875313 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Erlotinib in Treating Patients With Metastatic and/or Recurrent Head and Neck Cancer
NCT00281866 ·Status: COMPLETED ·Phase: PHASE2
-
Celecoxib in Treating Patients With Progressive Metastatic Differentiated Thyroid Cancer
NCT00061906 ·Status: COMPLETED ·Phase: PHASE2
-
Nelfinavir Mesylate in Treating Patients With Recurrent, Metastatic, or Unresectable Liposarcoma
NCT00233948 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Entinostat and Sorafenib Tosylate in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory or Relapsed Acute Myeloid Leukemia
NCT01159301 ·Status: TERMINATED ·Phase: PHASE1
-
A Study of TAS0612 in Participants With Advanced or Metastatic Solid Tumor Cancer
NCT04586270 ·Status: TERMINATED ·Phase: PHASE1
-
Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma
NCT00245102 ·Status: COMPLETED ·Phase: PHASE2
-
Thalidomide in Treating Patients With Metastatic Neuroendocrine Tumors
NCT00027638 ·Status: COMPLETED ·Phase: PHASE2
-
Sorafenib in Treating Patients With Metastatic or Unresectable Solid Tumors, Multiple Myeloma, or Non-Hodgkin's Lymphoma With or Without Impaired Liver or Kidney Function
NCT00118170 ·Status: COMPLETED ·Phase: PHASE1
-
Study of the EZH2 Inhibitor Tazemetostat in Malignant Mesothelioma
NCT02860286 ·Status: COMPLETED ·Phase: PHASE2