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Effects of an Oral GH Secretagogue (MK-677) on Body Composition and Functional Ability of Older Adults

NCT00474279 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 72

Last updated 2007-05-16

No results posted yet for this study

Summary

The purpose of this study is to determine whether treatment of healthy older men and women with oral MK-677 for 12 months will enhance pulsatile GH release and increase mean GH and IGF-I concentrations into the range of young adults and will have favorable effects on body composition and functional ability on older adults.

Conditions

  • Aging

Interventions

DRUG

Orally active growth hormone secretagogue (MK-677)

Sponsors & Collaborators

  • University of Virginia

    lead OTHER

Principal Investigators

  • Michael O. Thorner, MBBS, DSc, · University of Virginia

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
1998-07-31
Completion
2004-06-30

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00474279 on ClinicalTrials.gov