Improving Basic and Social Cognition in Veterans With Schizophrenia

NCT00470106 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 85

Last updated 2016-04-22

Study results available
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Summary

Veterans with schizophrenia and schizoaffective disorder experience very high levels of disability and poor community outcome. Further improvements in community outcome for patients with these disorders will not occur simply through better control of clinical symptoms. Instead, it will be necessary to find treatments that address the key determinants of poor functional outcome. Evidence strongly suggests that basic (non-social) cognitive and social cognitive deficits are among the key determinants of functional outcome for these illnesses. The primary goal of this 2-year pilot study is to implement and validate a new remediation program for social cognition that is appropriate for veterans with schizophrenia and schizoaffective disorder.

Conditions

Interventions

BEHAVIORAL

Cognitive remediation

Computer exercises in attention, memory, and speed of processing.

BEHAVIORAL

Social Cognitive skills training

Group training on emotion perception, social perception, and understanding others' mental states.

BEHAVIORAL

hybrid intervention

A combination of the two groups listed above.

BEHAVIORAL

skills training

Skills training in how to identify symptoms of illness and medication side effects.

Sponsors & Collaborators

  • VA Office of Research and Development

    lead FED

Principal Investigators

  • Michael F Green, PhD · VA Greater Los Angeles Healthcare System, West Los Angeles, CA

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-09-30
Primary Completion
2009-09-30
Completion
2009-09-30

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00470106 on ClinicalTrials.gov