MedTrace Logo

Tetracycline (Doxycycline) and Post Myocardial Infarction Remodeling

NCT00469261 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 110

Last updated 2012-09-25

No results posted yet for this study

Summary

The aim of the study is to assess the efficacy of an antibiotic treatment with tetracycline (doxycycline) in the early stage of large reperfused acute myocardial infarction (AMI), in preventing left ventricular (LV) remodeling.

Conditions

Interventions

DRUG

Doxycycline

Doxycycline 100 mg bid for seven days after enrollment

DRUG

Current medical therapy for AMI

Current medical therapy for AMI

Sponsors & Collaborators

  • Careggi Hospital

    lead OTHER

Principal Investigators

  • Giampaolo Cerisano, MD · Careggi Hospital, Florence, Italy

  • David Antoniucci, MD · Careggi Hospital, Florence, Italy

  • Piergiovanni Buonamici, MD · Careggi Hospital, Florence, Italy

  • Emilio V Dovellini, MD · Careggi Hospital, Florence, Italy

  • Alberto Santini, MD · Careggi Hospital, Florence, Italy

  • Umberto Signorini, MD · Careggi Hospital, Florence, Italy

  • Nazario Carrabba, MD · Careggi Hospital, Florence, Italy

  • Paolo D Pucci, MD · Careggi Hospital, Florence, Italy

  • Renato Valenti, MD · Careggi Hospital , Florence, Italy

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-05-31
Primary Completion
2011-08-31
Completion
2011-08-31

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00469261 on ClinicalTrials.gov