Asymptomatic Bacterial Vaginosis and Herpes Simplex Virus Type 2 (BV/HSV-2) Shedding Study
NCT00464542 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2017-05-11
Summary
This investigation assessed the effects of asymptomatic BV on daily genital tract shedding of HSV-2 by determining shedding frequency before and after treatment of asymptomatic BV.
Conditions
- Bacterial Vaginosis
Interventions
- DRUG
-
Metronidazole
500 mg, taken by mouth, two times a day, 7 days
Sponsors & Collaborators
-
University of Pittsburgh
lead OTHER
Principal Investigators
-
Thomas L Cherpes · Univerisity of Pittsburgh
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Max Age
- 26 Years
- Sex
- FEMALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2007-12-31
- Primary Completion
- 2010-03-31
- Completion
- 2010-03-31
Countries
- United States
Study Locations
More Related Trials
-
Evaluating New Formulation of Therapeutic HSV-2 Vaccine
NCT02515175 ·Status: COMPLETED ·Phase: PHASE2
-
A Multicenter, Double Blind, Comparative Study of Zidovudine Alone Versus Zidovudine and Acyclovir as Treatment for HIV-Infected Patients With CD4+ Counts Less Than 200 Cells/mm3
NCT00000712 ·Status: COMPLETED ·Phase: PHASE2
-
A Randomized Trial to Evaluated the Suppressive Effect of Acyclovir on Rapidly Cleared HSV-2 Reactivation
NCT00723229 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Efficacy Study of Herpes Simplex Virus Type 2 (HSV-2) Therapeutic DNA Vaccine
NCT02837575 ·Status: COMPLETED ·Phase: PHASE2
-
Valaciclovir to Prevent Transmission of Herpes Simplex Virus
NCT00001649 ·Status: COMPLETED ·Phase: PHASE3
-
A Clinical Trial in Healthy Volunteers and Volunteers With Recurrent Genital Herpes to Study the Safety, Tolerability, and Immune Responses After Vaccination With an Investigational Vaccine Designed to Prevent Genital Herpes Lesions
NCT05432583 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BAL
NCT06134492 ·Status: RECRUITING ·Phase: PHASE3
-
A Study to Assess the Safety, Pharmacokinetics, and Tolerability of ABI-1179 in Healthy Subjects and in Subjects Seropositive for HSV-2 With Recurrent Genital Herpes
NCT06698575 ·Status: COMPLETED ·Phase: PHASE1
-
An Epidemiological Study to Assess Performance of Using Healthcare Tools to Understand Genital Herpes Simplex Virus-2 (HSV-2) in Patients ≥ 18 Years of Age in the United States and Europe.
NCT04950712 ·Status: COMPLETED
-
Evaluating Three Grams Daily Valacyclovir in Patients With Chronic Hepatitis C and HSV-2 Infection (Phase I)
NCT01453075 ·Status: COMPLETED ·Phase: PHASE1
-
Dose Ranging Safety and Efficacy of Therapeutic HSV-2 Vaccine
NCT02114060 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Valacyclovir to Suppress HSV and HIV Shedding in Coinfected Persons
NCT00161434 ·Status: COMPLETED ·Phase: PHASE4
-
HSV-2 Suppression to Reduce HIV-1 Levels in HIV-1 Co-infected Persons
NCT00465205 ·Status: COMPLETED ·Phase: PHASE3
-
Acyclovir Therapy for Genital Herpes Ulcers in HIV Negative African Women
NCT02053142 ·Status: COMPLETED ·Phase: NA
-
Suppression of Oral HHV8 Shedding With Valganciclovir
NCT00194467 ·Status: COMPLETED ·Phase: PHASE2
-
Herpes Simplex Type 1 Suppression in Hepatitis C
NCT01580995 ·Status: COMPLETED ·Phase: PHASE2
-
The Effect of Acyclovir Treatment of the Herpes Simplex Virus (HSV) Infection on HIV Levels in the Blood
NCT00001115 ·Status: COMPLETED ·Phase: NA
-
Safety of a Herpes Simplex Candidate Vaccine (gD2t) With MPL and Its Efficacy to Prevent Genital Herpes Disease
NCT00699764 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of HSV-2 Suppressive Therapy on Sexual Behavior
NCT00495716 ·Status: TERMINATED ·Phase: PHASE4
-
Evaluating Safety and Efficacy of Repeat Doses of UB-621in Adult Patients With Recurrent Genital Herpes
NCT04979975 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Herpes Simplex Type 2 Co-infection in Veterans With Chronic Hepatitis C
NCT01037621 ·Status: UNKNOWN ·Phase: PHASE1
-
A Study on the Reactogenicity, Safety and Immune Response of a Vaccine Against Herpes Simplex Virus (HSV)-2 in Healthy Participants Aged 18-40 Years
NCT04762511 ·Status: TERMINATED ·Phase: PHASE1
-
Effectiveness of Acyclovir in Suppressing HIV Viral Load in Women Coinfected With HIV and Herpes Simplex Virus Type 2 (HSV-2)
NCT00371592 ·Status: COMPLETED ·Phase: PHASE2
-
Study of 2LHERP® in Genital Herpes Infections
NCT04235322 ·Status: TERMINATED ·Phase: PHASE4
-
Trial on Efficacy and Safety of Pritelivir Ointment for Treatment of Labial Herpes
NCT02871492 ·Status: COMPLETED ·Phase: PHASE2