Alemtuzumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia in Partial Remission or Complete Remission
NCT00458523 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 54
Last updated 2013-08-12
Summary
RATIONALE: Monoclonal antibodies, such as alemtuzumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them.
PURPOSE: This phase II trial is studying the side effects and how well alemtuzumab works in treating patients with B-cell chronic lymphocytic leukemia in partial remission or complete remission.
Conditions
Interventions
- BIOLOGICAL
-
alemtuzumab
- GENETIC
-
fluorescence in situ hybridization
- GENETIC
-
mutation analysis
- OTHER
-
flow cytometry
Sponsors & Collaborators
-
Leeds Cancer Centre at St. James's University Hospital
lead OTHER
Principal Investigators
-
Peter Hillmen, MD · Leeds General Infirmary
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-12-31
- Completion
- 2008-02-29
Countries
- United Kingdom
Study Locations
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