A Phase II Trial of Perifosine Following Tyrosine Kinase Inhibitor (TKI) - Failure in Patients With Renal Cancer
NCT00448721 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 24
Last updated 2018-03-01
Summary
This is a single-arm phase II trial of perifosine in renal cancer patients who have experienced disease progression after receiving either sorafenib or sunitinib.
Conditions
Interventions
- DRUG
-
Perifosine
Perifosine will be administered orally at 100mg PO daily with food.
Sponsors & Collaborators
- collaborator OTHER
-
AEterna Zentaris
lead INDUSTRY
Principal Investigators
-
Daniel Cho, MD · Dana-Farber Cancer Institute
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-03-31
- Primary Completion
- 2010-10-31
- Completion
- 2011-10-31
Countries
- United States
Study Locations
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