Effect of Ischemic Postconditioning on Targeting of Annexin A5 After Forearm Exercise
NCT00441714 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL
Last updated 2015-11-10
Summary
To adjust our forearm model for ischemia reperfusion injury, in order to used it for assessment of ischemia reperfusion damage in elderly and patients.
To test the effect of ischemic postconditioning on ischemia reperfusion injury in healthy volunteers, using Annexin binding after repetitive handgripping.
Conditions
- Cardiovascular Disease
- Ischemia-reperfusion Injury
- Postconditioning
Interventions
- PROCEDURE
-
repetitive short ischemia and reperfusion of non dominant fore arm after 10 minute ischemic exercise
Sponsors & Collaborators
-
Radboud University Medical Center
lead OTHER
Principal Investigators
-
Gerard Rongen, MD PhD · RUMCN
Study Design
- Allocation
- RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 50 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2007-10-31
- Completion
- 2007-12-31
Countries
- Netherlands
Study Locations
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