A Study To Evaluate The Effect Of WELLBUTRIN XL On Intraocular Pressure
NCT00439868 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 33
Last updated 2017-08-10
Summary
This study will be conducted in healthy volunteers to investigate the effect on intraocular pressure of 2 weeks of treatment with 300mg WELLBUTRIN XL/day.
Conditions
- Depressive Disorder
Interventions
- DRUG
-
WellbutrinXL
WELLBUTRIN XL tablets will be available with dose strength of 150 and 300 mg.
- DRUG
-
Matching placebo tablets to WELLBUTRIN XL.
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
GSK Clinical Trials · GlaxoSmithKline
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- DIAGNOSTIC
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2007-02-16
- Primary Completion
- 2007-06-08
- Completion
- 2007-06-08
Countries
- United States
Study Locations
More Related Trials
-
Clinical Study of Generic and Brand Bupropion in Depression
NCT02209597 ·Status: COMPLETED ·Phase: PHASE4
-
Vortioxetine, 5, 10, and 20 mg, Relapse Prevention Study in Adults With Major Depressive Disorder (MDD)
NCT02371980 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of Orcinoside With Placebo in Treatment of MDD
NCT02191384 ·Status: COMPLETED ·Phase: PHASE2
-
Seasonal Affective Depression (SAD) Study
NCT00069459 ·Status: COMPLETED ·Phase: PHASE1
-
Prevention of Seasonal Affective Disorder
NCT00046241 ·Status: COMPLETED ·Phase: PHASE3
-
Phase 1 Study to Assess the Safety/Tolerability of Brexpiprazole as Adjunctive Therapy in Elderly Subjects With Major Depressive Disorder
NCT01670279 ·Status: COMPLETED ·Phase: PHASE1
-
Study of the Efficacy and Safety of Initial Administration of 17 mg Vortioxetine Intravenously With 10 mg/Day Vortioxetine Orally in Patients With Major Depressive Disorder
NCT02919501 ·Status: COMPLETED ·Phase: PHASE2
-
A Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adults With Major Depressive Disorder
NCT03538691 ·Status: COMPLETED ·Phase: PHASE3
-
Effects of Bupropion in Depression
NCT02104128 ·Status: COMPLETED ·Phase: NA
-
Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment
NCT01838681 ·Status: COMPLETED ·Phase: PHASE3
-
Sexual Functioning Study With Antidepressants
NCT00316160 ·Status: COMPLETED ·Phase: PHASE4
-
Prevention of Seasonal Affective Disorder
NCT00046449 ·Status: COMPLETED ·Phase: PHASE3
-
Assessing Symptomatic Clinical Episodes in Depression
NCT03595579 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
NCT06223880 ·Status: RECRUITING ·Phase: PHASE4
-
A Trial of AXS-05 in Patients With Major Depressive Disorder
NCT04019704 ·Status: COMPLETED ·Phase: PHASE3
-
A Trial of Dextromethorphan and Bupropion Sustained-Release Tablets in Patients With Major Depressive Disorder
NCT06958692 ·Status: RECRUITING ·Phase: PHASE3
-
Safety and Efficacy of Vortioxetine (Lu AA21004) in Adults With Major Depressive Disorder
NCT01153009 ·Status: COMPLETED ·Phase: PHASE3
-
A Home-based Study Using Mobile Technology to Test Whether BI 1358894 is Effective in People With Depression
NCT04423757 ·Status: TERMINATED ·Phase: PHASE2
-
Efficacy, Safety and Tolerability of Agomelatine Sublingual Tablets in the Treatment of Major Depressive Disorder (MDD)
NCT01110902 ·Status: COMPLETED ·Phase: PHASE3
-
A Study to Assess the Safety of Repeated Doses of GSK189075 and WELLBUTRIN SR in Healthy Male Subjects
NCT00625859 ·Status: COMPLETED ·Phase: PHASE1
-
Open-Label Safety Study of AXS-05 in Subjects With Depression
NCT04039022 ·Status: COMPLETED ·Phase: PHASE3
-
To Demonstrate the Relative Bioavailability of Bupropion HCI 100 mg Tablets Under Fasting Conditions
NCT00883155 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Safety, Tolerability and Pharmacokinetics of NRX-1074 in Normal Healthy Volunteers
NCT02366364 ·Status: COMPLETED ·Phase: PHASE1
-
The Safety and Efficacy of Brexpiprazole as Adjunctive Therapy in the Treatment of Major Depressive Disorder
NCT03487198 ·Status: TERMINATED ·Phase: PHASE3
-
Efficacy and Safety of Brexpiprazole as Adjunctive Treatment in Elderly Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment
NCT01837797 ·Status: TERMINATED ·Phase: PHASE3