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Characterization of Clonal B Cell Populations in HCV Infection

NCT00435201 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 14

Last updated 2013-08-09

No results posted yet for this study

Summary

The purpose of this study is to investigate the mechanism of autoantibody production during chronic hepatitis C virus (HCV) infection. 10-50% of individuals with HCV have symptoms of mixed cryoglobulinemia (MC). By studying the B cells from HCV-infected individuals with and without MC, as well as from healthy controls, we hope to gain insight into the mechanisms of autoantibody production and develop new strategies for treatment of MC.

Conditions

  • Hepatitis C

Sponsors & Collaborators

  • New York Presbyterian Hospital

    collaborator OTHER

  • Rockefeller University

    lead OTHER

Principal Investigators

  • Lynn Dustin, PhD · Rockefeller University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-01-31
Primary Completion
2013-06-30
Completion
2013-06-30

Countries

  • United States
  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00435201 on ClinicalTrials.gov