Combination Trial of Patupilone and Carboplatin in Adult Patients With Advanced Solid Tumors
NCT00426582 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 48
Last updated 2020-12-09
Summary
This study will evaluate the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of patupilone combined with carboplatin in adult patients with advanced solid tumors who progressed despite standard therapy or for whom no standard therapy exists or who might benefit from treatment with carboplatin
Conditions
Interventions
- DRUG
-
Patupilone
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Novartis Pharmaceuticals · Novartis Pharmeceuticals
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-08-31
- Primary Completion
- 2010-08-31
Countries
- United States
Study Locations
More Related Trials
-
Topotecan and Carboplatin in the First-Line Treatment of Patients With Extensive Stage Small Cell Lung Cancer
NCT00305942 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan and Carboplatin as First-Line Therapy in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00469898 ·Status: COMPLETED ·Phase: PHASE2
-
First-line Treatment Of Subjects With Extensive Disease Small Cell Lung Cancer With Weekly Hycamtin And Paraplatin
NCT00316186 ·Status: COMPLETED ·Phase: PHASE2
-
Specialized Radiation Therapy and Chemotherapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery
NCT01486602 ·Status: COMPLETED ·Phase: PHASE1
-
High-Dose or Low-Dose Vorinostat in Combination With Carboplatin or Paclitaxel in Treating Patients With Advanced Solid Tumors
NCT01281176 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Polyglutamate Paclitaxel Plus Carboplatin Compared With Paclitaxel Plus Carboplatin in Treating Patients With Advanced or Recurrent Non-Small Cell Lung Cancer
NCT00054210 ·Status: TERMINATED ·Phase: PHASE3
-
Gemcitabine and Carboplatin With or Without AZD2171 as First-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
NCT00326599 ·Status: COMPLETED ·Phase: PHASE2
-
A Study for Small Cell Lung Cancer (SCLC) in Extensive Disease Stage
NCT00168896 ·Status: UNKNOWN ·Phase: PHASE2/PHASE3
-
Trial of Paclitaxel/Carboplatin + PF-3512676 vs Paclitaxel/Carboplatin Alone in Patients With Advanced Non-Small Cell Lung Cancer
NCT00254891 ·Status: TERMINATED ·Phase: PHASE3
-
PH 1 Evaluation Of Oral CI-1033 In Combination With Paclitaxel/ Carboplatin As 1st Line Chemotherapy In NSCLC Patients
NCT00174356 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Advanced Non-Small Cell Lung Cancer
NCT00041314 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer
NCT00032032 ·Status: COMPLETED ·Phase: PHASE1
-
Chemotherapy in Treating Patients With Non-Small Cell Lung Cancer
NCT00520676 ·Status: COMPLETED ·Phase: PHASE3
-
Study of NOV-002 in Combination With Chemotherapy to Treat Lung Cancer
NCT00347412 ·Status: COMPLETED ·Phase: PHASE3
-
Carboplatin, Paclitaxel, and Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed During Surgery
NCT00003387 ·Status: COMPLETED ·Phase: PHASE3
-
Dose Escalating Study of the Safety and Efficacy of Patupilone, q3w, in Patients With Non-small Cell Lung Cancer
NCT00171834 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Paclitaxel and Oxaliplatin in Treating Patients With Recurrent or Advanced Non-small Cell Lung Cancer
NCT00004126 ·Status: COMPLETED ·Phase: PHASE2
-
A Trial of SHR-1316/Placebo in Combination With Chemotherapy in Patients With Resectable NSCLC
NCT04316364 ·Status: RECRUITING ·Phase: PHASE3
-
Study of Patupilone in Patients With Brain Metastasis From Non-small Cell Lung Cancer
NCT00219297 ·Status: COMPLETED ·Phase: PHASE2
-
S0342: Paclitaxel, Carboplatin, and Cetuximab in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
NCT00085501 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Stage IIIB, Stage IV, or Recurrent Non-Small Cell Lung Cancer
NCT00054392 ·Status: WITHDRAWN ·Phase: PHASE3
-
Study of Carboplatin/Paclitaxel With or Without Investigational Drug (CS-7017) in Subjects With Metastatic Non-small Cell Lung Cancer
NCT00806286 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Atezolizumab in Combination With Carboplatin + Paclitaxel or Carboplatin + Nab-Paclitaxel Compared With Carboplatin + Nab-Paclitaxel in Participants With Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC) [IMpower131]
NCT02367794 ·Status: COMPLETED ·Phase: PHASE3
-
Carboplatin and Gemcitabine With Bevacizumab Every 2 Weeks for Stage IIIb/IV Non-small Cell Lung Cancer
NCT00400803 ·Status: COMPLETED ·Phase: PHASE2
-
A Trial of Carboplatin and Gemcitabine Versus Gemcitabine Alone in Patients With Non-Small-Cell Lung Cancer
NCT00190710 ·Status: COMPLETED ·Phase: PHASE3