Phase I/II Study of hLL1 in Multiple Myeloma
NCT00421525 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2021-08-16
Summary
This is a Phase I/II, open-label, multi-center study conducted in patients with recurrent or refractory multiple myeloma who have failed at least two prior standard systemic treatments.
Conditions
- Multiple Myeloma
- Myeloma, Plasma-Cell
- PLASMACYTOMA
Interventions
- BIOLOGICAL
-
milatuzumab
twice weekly dosing for 4 weeks, total of 8 doses
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
William Wegener, MD, PhD · Gilead Sciences
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2007-01-31
- Primary Completion
- 2009-06-30
- Completion
- 2009-06-30
Countries
- United States
Study Locations
More Related Trials
-
BB-10901 in Treating Patients With Relapsed and/or Refractory Multiple Myeloma
NCT00346255 ·Status: COMPLETED ·Phase: PHASE1
-
Determining the Feasibility of MLN9708 as Maintenance After Allogeneic Stem Cell Transplant for Multiple Myeloma
NCT02168101 ·Status: COMPLETED ·Phase: PHASE2
-
An Efficacy and Safety Study of Siltuximab in Participants With Relapsed or Refractory Multiple Myeloma
NCT00402181 ·Status: COMPLETED ·Phase: PHASE2
-
Outpatient and Intermittent Dosing of Elranatamab in Relapsed/Refractory Multiple Myeloma
NCT06421675 ·Status: RECRUITING ·Phase: PHASE2
-
AZD6244 (Selumetinib) in Treating Patients With Multiple Myeloma
NCT01085214 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Anitocabtagene-autoleucel in Participants With Relapsed Refractory Multiple Myeloma
NCT04155749 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Lenalidomide and High Dose Melphalan Followed by Autologous Stem Cell Transplant in Multiple Myeloma
NCT01142232 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Frontline Therapy in de Novo Multiple Myeloma Patients Under 65
NCT01206205 ·Status: COMPLETED ·Phase: PHASE2
-
Daratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma
NCT03346135 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Phase 2 Study of Carfilzomib in Relapsed Multiple Myeloma
NCT00530816 ·Status: COMPLETED ·Phase: PHASE2
-
Use of Elranatamab in Patients With High-risk Smoldering Multiple Myeloma
NCT06183489 ·Status: RECRUITING ·Phase: PHASE2
-
A Phase 1/2a Dose-Finding Study of PT-112 in Patients With Relapsed or Refractory Multiple Myeloma
NCT03288480 ·Status: COMPLETED ·Phase: PHASE1
-
S1211 Bortezomib, Dexamethasone, and Lenalidomide With or Without Elotuzumab in Treating Patients With Newly Diagnosed High-Risk Multiple Myeloma
NCT01668719 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study Evaluating Temsirolimus (CCI-779) In Mantle Cell Lymphoma (MCL)
NCT00117598 ·Status: COMPLETED ·Phase: PHASE3
-
Daratumumab in Treating Transplant-Eligible Patients With Multiple Myeloma
NCT03477539 ·Status: COMPLETED ·Phase: PHASE2
-
MMRC Horizon One Adaptive Platform Trial Evaluating Therapies in RRMM
NCT06171685 ·Status: RECRUITING ·Phase: PHASE2
-
Efficacy and Safety Study of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma
NCT03361748 ·Status: COMPLETED ·Phase: PHASE2
-
Lenalidomide in Treating Patients With Progressive or Recurrent Multiple Myeloma After a Donor Stem Cell Transplant
NCT00619684 ·Status: COMPLETED ·Phase: PHASE2
-
a Clinical Trial of Efficacy and Safety of the Holistic Treatment of Young High-risk Multiple Myeloma Patients
NCT04008888 ·Status: UNKNOWN ·Phase: NA
-
Study of Oral Ixazomib in Adult Participants With Relapsed and/or Refractory (RR) Multiple Myeloma
NCT00932698 ·Status: COMPLETED ·Phase: PHASE1
-
Tipifarnib and Bortezomib in Treating Patients With Relapsed Multiple Myeloma
NCT00243035 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
A Study of mRNA-2808 in Participants With Relapsed or Refractory Multiple Myeloma
NCT07116616 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Lenalidomide in Treating Patients With Multiple Myeloma Undergoing Autologous Stem Cell Transplant
NCT00114101 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma in African-American and European-American Patients
NCT05014646 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study to Evaluate Subcutaneous Daratumumab in Combination With Standard Multiple Myeloma Treatment Regimens
NCT03412565 ·Status: COMPLETED ·Phase: PHASE2