Trial Outcomes & Findings for Recovery of Visual Acuity in People With Vestibular Deficits (NCT NCT00411216)

Results Overview

visual acuity is measured using a computerized system first with the head stationary and then with the head moving in yaw plane. Head velocity is measured using a rate sensor and optotype is displayed only when head velocity is between 120 and 180 degrees per second. The change in visual acuity was calculated from subtracting the discharge measurement from the baseline measurement (pre-intervention).

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

23 participants

Primary outcome timeframe

pre-intervention and at discharge

Results posted on

2015-08-07

Participant Flow

Participant milestones

Participant milestones
Measure	Exercises for Gaze Stabilization Experimental group performed vestibular adaptation and substitution exercises gaze stabilization exercises: adaptation and substitutin exercises encorporating retinal lsip and head movements	Control Exercises Saccadic eye movements against a Ganzfeld to prevent retinal slip error signal; no head movements Control exercises: saccadic eye movements against a plain background; no head movements
Overall Study STARTED	13	10
Overall Study COMPLETED	13	8
Overall Study NOT COMPLETED	0	2

Reasons for withdrawal

Reasons for withdrawal
Measure	Exercises for Gaze Stabilization Experimental group performed vestibular adaptation and substitution exercises gaze stabilization exercises: adaptation and substitutin exercises encorporating retinal lsip and head movements	Control Exercises Saccadic eye movements against a Ganzfeld to prevent retinal slip error signal; no head movements Control exercises: saccadic eye movements against a plain background; no head movements
Overall Study Ten participants were entered into the c	0	2

Baseline Characteristics

Recovery of Visual Acuity in People With Vestibular Deficits

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Exercises for Gaze Stabilization n=13 Participants Experimental group performed gaze stabilization exercises: adaptation and substitution exercises encorporating retinal slip and head movements	Control Exercises n=10 Participants Saccadic eye movements against a Ganzfeld to prevent retinal slip error signal; no head movements	Total n=23 Participants Total of all reporting groups
Age, Continuous	65.2 years STANDARD_DEVIATION 16.5 • n=99 Participants	64.9 years STANDARD_DEVIATION 16.2 • n=107 Participants	65.1 years STANDARD_DEVIATION 16.3 • n=206 Participants
Age, Categorical <=18 years	0 Participants n=99 Participants	0 Participants n=107 Participants	0 Participants n=206 Participants
Age, Categorical Between 18 and 65 years	6 Participants n=99 Participants	5 Participants n=107 Participants	11 Participants n=206 Participants
Age, Categorical >=65 years	7 Participants n=99 Participants	5 Participants n=107 Participants	12 Participants n=206 Participants
Sex: Female, Male Female	9 Participants n=99 Participants	6 Participants n=107 Participants	15 Participants n=206 Participants
Sex: Female, Male Male	4 Participants n=99 Participants	4 Participants n=107 Participants	8 Participants n=206 Participants
Region of Enrollment United States	13 participants n=99 Participants	10 participants n=107 Participants	23 participants n=206 Participants
Visual acuity during head movements	.372 LogMAR STANDARD_DEVIATION .155 • n=99 Participants	.323 LogMAR STANDARD_DEVIATION .117 • n=107 Participants	.348 LogMAR STANDARD_DEVIATION .136 • n=206 Participants

PRIMARY outcome

Timeframe: pre-intervention and at discharge

visual acuity is measured using a computerized system first with the head stationary and then with the head moving in yaw plane. Head velocity is measured using a rate sensor and optotype is displayed only when head velocity is between 120 and 180 degrees per second. The change in visual acuity was calculated from subtracting the discharge measurement from the baseline measurement (pre-intervention).