A 52-Week Study to Assess the Effects of MK0822 on Knee Osteoarthritis (MK-0822-011)
NCT00397683 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 2
Last updated 2015-11-02
Summary
The purpose of this study is to test MK0822 on disease activity in patients with osteoarthritis in the knee. Disease modifying activity of MK0822 will be assessed by measurements of knee cartilage using Magnetic Resonance Imaging (MRI) of the knee.
This is an early phase trial and some specific protocol information is proprietary and not publicly available at this time. (Full information is available to trial participants).
Conditions
Interventions
- DRUG
-
MK0822
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Medical Monitor · Merck Sharp & Dohme LLC
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-10-31
- Primary Completion
- 2007-04-30
- Completion
- 2007-04-30
Countries
- United States
- Chile
- Colombia
- Mexico
- Poland
Study Locations
More Related Trials
-
Long-Term Effects of Mobithron Advance on Knee Osteoarthritis Aims to Investigate the Effects of Mobithron Advance on OA Progression
NCT07323745 ·Status: NOT_YET_RECRUITING ·Phase: EARLY_PHASE1
-
Osteoarthritis Initiative (OAI): A Knee Health Study
NCT00080171 ·Status: COMPLETED
-
A Study of MEDI7352 in Painful Osteoarthritis of the Knee
NCT02508155 ·Status: COMPLETED ·Phase: PHASE1
-
A Study of the Efficacy and Safety of MEDI7352 in Participants With Painful Osteoarthritis of the Knee
NCT04675034 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Assess MEDI -578 in Patients With Osteoarthritis (OA) of the Knee
NCT01072591 ·Status: TERMINATED ·Phase: PHASE1
-
A Multicenter Study of rhFGF 18 in Patients With Knee Osteoarthritis Not Requiring Surgery
NCT01033994 ·Status: COMPLETED ·Phase: PHASE1
-
Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee
NCT02205814 ·Status: COMPLETED ·Phase: PHASE2
-
Study of AS902330 (rhFGF-18) Administered Intra-articularly in Patients With Knee Primary Osteoarthritis Who Are Candidates for Total Knee Replacement
NCT00911469 ·Status: COMPLETED ·Phase: PHASE1
-
A Study Evaluating the Safety, Tolerability, and Range of Biologically Active Doses of ICM-203 in Mild to Moderate Knee Osteoarthritis
NCT04875754 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
A Safety, Tolerability, Pharmacokinetics (PK) and Target Engagement (TE) Study of GSK3858279 in Healthy Participants and Evaluation of the Efficacy of Repeat Doses in Participants With Osteoarthritis (OA)
NCT03485365 ·Status: COMPLETED ·Phase: PHASE1
-
Etoricoxib in the Treatment of Osteoarthritis (MK-0663-007)
NCT00242489 ·Status: COMPLETED ·Phase: PHASE2
-
Study to Evaluate the Safety and Tolerability of FX201 in Patients with Osteoarthritis of the Knee
NCT04119687 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A First-in-human Study to Investigate Safety and Tolerability of SAR446959 in Participants With Osteoarthritis of the Knee
NCT06704932 ·Status: COMPLETED ·Phase: PHASE1
-
Study to Evaluate the Effect of FX006 on Synovial Inflammation in Patients With OA of the Knee
NCT03529942 ·Status: COMPLETED ·Phase: PHASE3
-
Study of the Effect of Chondroitin Sulfate on Structural Changes in Knee Osteoarthritis Patients Assessed by MRI
NCT01354145 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of MK0663 and an Approved Drug in the Treatment of Osteoarthritis (0663-076)(COMPLETED)
NCT00092768 ·Status: COMPLETED ·Phase: PHASE3
-
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 1026706 in Male and Female Healthy Subjects and Patients With Osteoarthritis of the Knee
NCT02126826 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate Safety and Tolerability of MIV-711 in Osteoarthritis Patients
NCT03037489 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of MK0663 and an Approved Drug in the Treatment of Osteoarthritis (0663-077)(COMPLETED)
NCT00092781 ·Status: COMPLETED ·Phase: PHASE3
-
Methotrexate in the Treatment of Advanced Knee Osteoarthritis With Effusion-synovitis
NCT03815448 ·Status: COMPLETED ·Phase: NA
-
52 Week, International, Multi-center, Randomized, Double-blind, Double-dummy, Parallel-group Clinical Trial to Compare Retention on Treatment, Safety, Tolerability & Efficacy of Lumiracoxib 100 mg od, Lumiracoxib 100 mg Bid & Celecoxib 200 mg od in Pts With Primary OA of Hip, Knee, Hand or Spine
NCT00145301 ·Status: COMPLETED ·Phase: PHASE3
-
Prospective Assessment of the Efficacy of Hyaluronate Knee Injections in Patients With Osteoarthritis
NCT00323778 ·Status: TERMINATED ·Phase: PHASE3
-
Efficacy and Safety of Lumiracoxib in Patients With Primary Knee Osteoarthritis (OA)
NCT00367315 ·Status: COMPLETED ·Phase: PHASE3
-
Safety, Tolerability, Pharmacokinetics and -Dynamics of Multiple Rising Oral Doses of BI 113823 in Patients Patients With Osteoarthritis of the Knee
NCT01207973 ·Status: TERMINATED ·Phase: PHASE1
-
12-Week No-Rofecoxib Plus Aspirin Endoscopy Study (0782-003)
NCT00543465 ·Status: TERMINATED ·Phase: PHASE2