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Penetrance of Third Generation Fluoroquinolones in Eyes With Functioning Filtering Blebs

NCT00392275 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 48

Last updated 2013-04-10

No results posted yet for this study

Summary

Based on previous results with eyes without filtering blebs, the aqueous concentrations of ofloxacin and levofloxacin will exceed the concentration of ciprofloxacin after either topical or topical plus oral administration.

Conditions

  • Cataract

Interventions

DRUG

Ofloxacin 0.3%

DRUG

Ciprofloxacin 0.3%

DRUG

Levofloxacin 0.5%

DRUG

Ofloxacin 400mg

DRUG

Ciprofloxacin 400mg

DRUG

Levofloxacin 250mg

Sponsors & Collaborators

  • Indiana University School of Medicine

    lead OTHER

Principal Investigators

  • Louis B Cantor, MD · Indiana University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-11-30
Completion
2006-05-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00392275 on ClinicalTrials.gov