PPI Sequencing Study
NCT00384592 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2009-03-11
Summary
The purpose of this study is to assess how patients with gastro-oesophageal reflux disease (heartburn) who are currently receiving treatment with a proton pump inhibitor but are still experiencing symptoms will benefit from a change in treatment.
Conditions
- Gastro-Oesophageal Reflux Disease
Interventions
- DRUG
-
Esomeprazole
- PROCEDURE
-
Physical exam
- PROCEDURE
-
Pregnancy test if applicable
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Rhiannon Rowsell, MD · AstraZeneca
-
Roger Jones, MD · UCL
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-09-30
- Primary Completion
- 2007-05-31
- Completion
- 2007-05-31
Countries
- United Kingdom
Study Locations
More Related Trials
-
Efficacy of Esomeprazole in Patients With Frequent Heartburn
NCT01370525 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy of Esomeprazole in Patients With Frequent Heartburn
NCT01370538 ·Status: COMPLETED ·Phase: PHASE3
-
Esomeprazole And Symptomatic Response In Patients With Or Without An Elevated Risk For Non-Steroidal Anti-Inflammatory Drug (NSAID)-Associated GI Damage
NCT00524329 ·Status: COMPLETED
-
On-demand PPI Therapy is Effective on Controlling Symptoms in Patients With Barrett's Esophagus.
NCT04329000 ·Status: COMPLETED ·Phase: NA
-
Reflux Esophagitis Phase III Study (Initial Treatment)
NCT00633932 ·Status: COMPLETED ·Phase: PHASE3
-
A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)
NCT03561090 ·Status: TERMINATED ·Phase: PHASE3
-
Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux Disease
NCT00829738 ·Status: COMPLETED
-
Pilot Study To Investigate The Association Between Acid Control And Heartburn Symptoms After Proton Pump Inhibitor Treatment
NCT02708355 ·Status: COMPLETED ·Phase: PHASE4
-
Barrett's Esophagus - 315 - 3 Way Cross-Over
NCT00637559 ·Status: COMPLETED ·Phase: PHASE4
-
Nexium Dyspepsia/AST
NCT00251992 ·Status: COMPLETED ·Phase: PHASE3
-
An Open Label pH Comparison of Esomeprazole and Lansoprazole in Barrett's Esophagus Patients
NCT00352261 ·Status: COMPLETED ·Phase: PHASE4
-
Proton Pump Inhibitor (PPI) Therapy for Newly Diagnosed Esophagitis
NCT00586963 ·Status: COMPLETED
-
Nexium Dyspepsia/AST
NCT00251914 ·Status: COMPLETED ·Phase: PHASE3
-
Reflux Esophagitis Phase III Study (Maintenance Treatment)
NCT00634114 ·Status: COMPLETED ·Phase: PHASE3
-
Study Comparing Esomeprazole Magnesium 40mg Once Daily Versus Lansoprazole 30 mg Twice Daily in Symptom Control of Subjects With Persistent Gastrooesophageal Reflux Disease (GERD)
NCT00637845 ·Status: COMPLETED ·Phase: PHASE4
-
Proton Pump Inhibitor (PPI) Inappropriate Use and Economic Burden in Chinese Population
NCT03118778 ·Status: COMPLETED
-
GSK1349572 Proton Pump Inhibitor Drug Interaction and Supratherapeutic Dose Study
NCT00942136 ·Status: COMPLETED ·Phase: PHASE1
-
Trans GERD: Efficacy and Tolerability of Esomeprazol in Patients Under Ordinary Medical Care Conditions
NCT00612027 ·Status: COMPLETED
-
To Assess the Efficacy of Esomeprazole 20mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole
NCT01397084 ·Status: COMPLETED ·Phase: PHASE4
-
Esomeprazole for Prevention of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDs
NCT00241514 ·Status: COMPLETED ·Phase: PHASE3
-
A Multicenter, Randomized, Double-Blind Parallel-Group, Placebo-Controlled Efficacy Study Comparing 4 Weeks of Treatment With Esomeprazole 20 mg Once Daily to Placebo qd for the Resolution of Upper Abdominal Pain in Patients With Symptomatic Gastroesophageal Reflux Disease (sGERD)
NCT00626535 ·Status: COMPLETED ·Phase: PHASE3
-
To Assess the Efficacy of Esomeprazole 40 mg Once Daily in Subjects Who Still Had Heartburn After Receiving Rabeprazole
NCT01249651 ·Status: COMPLETED ·Phase: PHASE4
-
Study Comparing the Effects of Esomeprazole Adminstered Orally and Intravenously on Basal and Pentrigastrin-stimulated Acid Output in Subjects With Symptoms of Gastroesophageal Reflux Disease (GERD)
NCT00625495 ·Status: COMPLETED ·Phase: PHASE4
-
Gastric Functions & Proton Pump Inhibitor( PPI) Study
NCT00951431 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Effect of Food, Formulation Strength, and a Proton Pump Inhibitor on GED 0301 Pharmacokinetics in Healthy Adult Subjects
NCT02957474 ·Status: COMPLETED ·Phase: PHASE1