IOP-Lowering Efficacy of Brinzolamide 1.0% Added to Travoprost 0.004%/Timolol 0.5% Fixed Combination as Adjunctive Therapy
NCT00382226 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 195
Last updated 2016-11-18
Summary
Uncontrolled glaucoma patients being treated with a prostaglandin agent alone or in combination with adjunctive drugs in fixed or unfixed combinations, will be switched from their current therapy to travoprost/timolol fixed combination and either Azopt or placebo
Conditions
Interventions
- DRUG
-
Azopt
Sponsors & Collaborators
-
Alcon Research
lead INDUSTRY
Principal Investigators
-
Mark Jasek · Alcon Research
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-09-30
- Primary Completion
- 2007-08-31
- Completion
- 2007-08-31
Countries
- Australia
Study Locations
More Related Trials
-
Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt
NCT01722604 ·Status: COMPLETED ·Phase: PHASE3
-
IOP Lowering Efficacy of Travoprost/Brinzolamide Fixed Combination Ophthalmic Suspension in Patients With Open-Angle Glaucoma or Ocular Hypertension
NCT00527501 ·Status: COMPLETED ·Phase: PHASE2
-
24-Hour Intraocular Pressure With Brinzolamide/Timolol Versus Brimonidine/Timolol
NCT00981786 ·Status: COMPLETED ·Phase: PHASE4
-
Phase IV Randomised Double-masked Clinical Trial: Assessing Morning Versus Evening Dosing of a Fixed Dose Combination of Travoprost 0.004% / Timolol Maleate 0.5% in Patients With Primary Open-angle Glaucoma or Ocular Hypertension
NCT00759239 ·Status: COMPLETED ·Phase: PHASE4
-
Fixed Combination Brinzolamide 1%/Timolol 0.5% Versus Brinzolamide 1% + Timolol 0.5% in Open-Angle Glaucoma or Ocular Hypertension
NCT01357616 ·Status: COMPLETED ·Phase: PHASE3
-
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
NCT00326092 ·Status: COMPLETED ·Phase: PHASE2
-
Travoprost/Brinzolamide Fixed Combination Versus Travatan and Versus AZOPT
NCT00767494 ·Status: TERMINATED ·Phase: PHASE3
-
Safety and Efficacy of Adding AZARGA® Adjunctive to Prostaglandin Therapy
NCT01263444 ·Status: COMPLETED ·Phase: PHASE4
-
Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID Plus Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension
NCT01309204 ·Status: COMPLETED ·Phase: PHASE3
-
Comparison of Intraocular Pressure (IOP)-Lowering Efficacy and Safety of AZORGA® Ophthalmic Suspension and COSOPT® Ophthalmic Solution
NCT02325518 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
NCT00333125 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy and Safety of Adding Azarga to Prostaglandin Monotherapy
NCT00966576 ·Status: COMPLETED ·Phase: PHASE4
-
Safety and Efficacy of Brinzolamide Dosed TID With Dorzolamide Dosed TID in Reducing Intraocular Pressure in Patients With Open Angle Glaucoma or Ocular Hypertension
NCT00761995 ·Status: COMPLETED ·Phase: PHASE4
-
A Phase IV Study of Travoprost + Brinzolamide to Treat Glaucoma or Ocular Hypertension
NCT00471380 ·Status: COMPLETED ·Phase: PHASE4
-
24-Hour Intraocular Pressure (IOP) Control With Travoprost/Timolol Fixed Combination
NCT00331240 ·Status: COMPLETED ·Phase: PHASE3
-
Efficacy of Travoprost/Timolol for Uncontrolled Intraocular Pressure
NCT02003391 ·Status: COMPLETED ·Phase: PHASE4
-
Bimatoprost Monotherapy vs. Dual Therapy With Travoprost and Timolol in Patients With Glaucoma and Ocular Hypertension
NCT00348023 ·Status: COMPLETED ·Phase: PHASE4
-
A Phase III Study of Travoprost/Timolol Combination in Patients With Open-Angle Glaucoma or Ocular Hypertension
NCT00672997 ·Status: COMPLETED ·Phase: PHASE3
-
Brinzolamide/Brimonidine Twice a Day (BID) Fixed Combination (FC) vs Brinzolamide BID and Brimonidine BID in Patients With Open Angle Glaucoma or Ocular Hypertension
NCT01310777 ·Status: COMPLETED ·Phase: PHASE3
-
Latanoprost/Brinzolamide BID Versus Latanoprost BID in Patients With OAG or OH
NCT01721707 ·Status: WITHDRAWN ·Phase: PHASE3
-
Comparison of Brimonidine Purite, Dorzolamide, and Brinzolamide as Adjunctive Therapy to Prostaglandin Analogs
NCT00675207 ·Status: COMPLETED ·Phase: PHASE4
-
Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension
NCT00822055 ·Status: COMPLETED ·Phase: PHASE4
-
Additive Effect of Twice-daily Brinzolamide 1%/Brimonidine 0.2%Combination as an Adjunctive Therapy to Travoprost in Patients With Normal Tension Glaucoma
NCT03150160 ·Status: COMPLETED ·Phase: PHASE4
-
Brinzolamide/Brimonidine Combination vs Brimonidine 0.2% in the Prevention of IOP Rise After Nd-YAG Laser Capsulotomy
NCT03192826 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of a Glaucoma Therapy to Treat Open-Angle Glaucoma or Ocular Hypertension
NCT00314171 ·Status: COMPLETED ·Phase: PHASE3