A Phase I Study of Pazopanib in Adult Patients With Liver Cancer
NCT00370513 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 28
Last updated 2017-11-17
Summary
Liver cancer is a good target for anti-angiogenic treatments such as pazopanib. The effect of pazopanib in patients with liver cancer are unknown. This study is designed to evaluate the safety, tolerability and best dose of pazopanib to be given to patient with liver cancer.
Conditions
- Carcinoma, Hepatocellular
Interventions
- DRUG
-
pazopanib
Pazopanib is a potent, multi-target receptor tyrosine kinase inhibitor of VEGFR.
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
GSK Clinical Trials · GlaxoSmithKline
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 21 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-12-06
- Primary Completion
- 2009-04-08
- Completion
- 2009-04-08
Countries
- United States
- Hong Kong
- Taiwan
Study Locations
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