Ispinesib in Treating Patients With Metastatic or Unresectable Kidney Cancer
NCT00354250 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 60
Last updated 2013-06-05
Summary
This phase II trial is studying how well ispinesib works in treating patients with metastatic or unresectable kidney cancer. Ispinesib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Conditions
- Recurrent Renal Cell Cancer
- Stage III Renal Cell Cancer
- Stage IV Renal Cell Cancer
Interventions
- DRUG
-
ispinesib
Given IV
Sponsors & Collaborators
-
National Cancer Institute (NCI)
lead NIH
Principal Investigators
-
Walter Stadler · University of Chicago Comprehensive Cancer Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-05-31
- Primary Completion
- 2007-02-28
Countries
- United States
Study Locations
More Related Trials
-
SU5416 and Interferon Alfa-2b in Treating Patients With Unresectable or Metastatic Kidney Cancer
NCT00006384 ·Status: COMPLETED ·Phase: PHASE2
-
Expanded Access Use of INCB054329 to Treat a Single Patient With Metastatic Renal Cell Carcinoma
NCT03896815 ·Status: NO_LONGER_AVAILABLE
-
Study of the Safety and Efficacy of SU-011,248 in Adult Patients With Advanced Kidney Cancer
NCT00054886 ·Status: COMPLETED ·Phase: PHASE2
-
SU5416 in Treating Patients With Metastatic Kidney Cancer That Has Not Responded to Previous Treatment
NCT00009919 ·Status: TERMINATED ·Phase: PHASE2
-
Nivolumab in Patients With Metastatic Renal Cell Carcinoma Who Have Progresses During or After Prior Systemic Anti-angiogenic Regimen
NCT03013335 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Metastatic Kidney Cancer
NCT00003683 ·Status: COMPLETED ·Phase: PHASE2
-
Nivolumab in Treating Patients With Localized Kidney Cancer Undergoing Nephrectomy
NCT03055013 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
PS-341 in Treating Patients With Metastatic Kidney Cancer
NCT00025376 ·Status: COMPLETED ·Phase: PHASE2
-
RP2 and Tivozanib for the Treatment of Metastatic Renal Cell Cancer After Progression on Immunotherapy
NCT07218692 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Study of IMO-2055 in Metastatic or Locally Recurrent Clear Cell Renal Carcinoma
NCT00729053 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Safety of Nivolumab and Ipilimumab in Subjects With Previously Untreated Advanced or Metastatic Renal Cell Cancer
NCT02982954 ·Status: COMPLETED ·Phase: PHASE4
-
Sunitinib in Treating Patients With Locally Recurrent or Metastatic Kidney Cancer
NCT00459875 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Entinostat With Nivolumab Plus Ipilimumab in Previously Treated Renal Cell Carcinoma
NCT03552380 ·Status: TERMINATED ·Phase: PHASE2
-
Sorafenib, Gemcitabine, and Capecitabine in Treating Patients With Unresectable and/or Metastatic Kidney Cancer
NCT00121251 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell Cancer
NCT02019693 ·Status: COMPLETED ·Phase: PHASE2
-
Cabozantinib-s-malate or Sunitinib Malate in Treating Patients With Previously Untreated Locally Advanced or Metastatic Kidney Cancer
NCT01835158 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of Sasanlimab, Palbociclib and Axitinib in Metastatic Renal Cell Carcinoma
NCT07123090 ·Status: RECRUITING ·Phase: PHASE2
-
Study Of Cabozantinib Treatment In Patients With Unresectable, Locally Advanced Or Metastatic Renal Cell Carcinoma Who Progressed After Previous Treatment With Checkpoint Inhibitors
NCT04353765 ·Status: COMPLETED
-
A Phase I/II Study to Assess the Safety and Efficacy of TKI258 for the Treatment of Refractory Advanced/Metastatic Renal Cell Cancer
NCT00715182 ·Status: COMPLETED ·Phase: PHASE1
-
Pazopanib Hydrochloride in Treating Patients With Metastatic Kidney Cancer Who Have No Evidence of Disease After Surgery
NCT01575548 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
A Study to Compare Treatments for a Type of Kidney Cancer Called TFE/Translocation Renal Cell Carcinoma (tRCC)
NCT03595124 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
UCN-01 in Treating Patients With Advanced or Metastatic Kidney Cancer
NCT00030888 ·Status: UNKNOWN ·Phase: PHASE2
-
Cediranib Maleate in Treating Patients With Recurrent or Metastatic Kidney Cancer That Cannot Be Removed By Surgery
NCT00227760 ·Status: COMPLETED ·Phase: PHASE2
-
Testing Cabozantinib, Crizotinib, Savolitinib and Sunitinib in Kidney Cancer Which Has Progressed
NCT02761057 ·Status: COMPLETED ·Phase: PHASE2
-
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
NCT07227415 ·Status: RECRUITING ·Phase: PHASE1/PHASE2