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Analgetic and Anxiolytic Effect of Preoperative Pregabalin

NCT00353704 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2011-07-20

Study results available
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Summary

The purpose of this study is to determine whether the use of oral pregabalin 150 mg as premedication reduces the amount and degree of postoperative pain.

Furthermore the purpose of this study is to determine whether the use of oral pregabalin 150 mg as premedication reduces anxiety prior to anaesthesia in these patients.

Conditions

  • Intervertebral Disk Displacement
  • Disk Prolapse

Interventions

DRUG

pregabalin

capsule 150 mg x 1 per orally one hour before surgery

DRUG

Placebo

One capsule of saccharose (placebo) was administered about one hour before surgery

DRUG

morphine

All patients were equipped with a PCA (patient controlled analgesia) for 24 hours after surgery. The sum of morphine used was registered (milligram).

Sponsors & Collaborators

  • Asker & Baerum Hospital

    lead OTHER

Principal Investigators

  • Ulrich J Spreng, Dr. med. · Asker and Baerum Hospital, Norway

  • Vegard Dahl, Dr. med. · Asker and Baerum Hospital, Norway

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-11-30
Primary Completion
2009-05-31
Completion
2010-06-30

Countries

  • Norway

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00353704 on ClinicalTrials.gov