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Efficacy of LASIK Versus PRK in Asians With Mild and Moderate Myopia

NCT00348049 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL

Last updated 2006-10-24

No results posted yet for this study

Summary

Laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) are currently the 2 main refractive surgeries to correct myopia which are being performed worldwide, with more patients preferring LASIK to PRK because of better comfort and faster rehabilitation. However, in post-LASIK patients, there is a low risk of flap dislodgement. This risk increases with certain occupations which have a higher risk of trauma. Hence, there may be a role for PRK for people which such occupations, e.g. soldiers, parachutists, sportsman.

There are several non-randomised studies which show that PRK is as efficacious, predictable and safe as LASIK for low to moderate myopes. But there have been only a few randomized controlled studies to compare the efficacy and safety of the 2 treatment modalities and all studies comparing LASIK and PRK suffer from a high dropout rate during the follow-up period. We compared the efficacy, predictability, stability and safety of LASIK versus PRK over a one year duration with almost 100% attendance during all follow-up visits.

Conditions

  • Myopia

Interventions

PROCEDURE

Laser in Situ Keratomileusis (LASIK)

PROCEDURE

Photorefractive Keratectomy (PRK)

Sponsors & Collaborators

  • Singapore Armed Forces

    collaborator UNKNOWN

  • Defence Medical Environmental Research Institute

    collaborator OTHER

  • Singapore National Eye Centre

    lead OTHER_GOV

Principal Investigators

  • Donald Tan, FAMS · Singapore Eye Research Institute

  • Benjamin Seet · Singapore Armed Forces

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
21 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-11-30
Completion
2005-08-31

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00348049 on ClinicalTrials.gov